Parul Punia, Antariksh Deep, Kausalya Raghuraman, Nidhi Goel, Uma Chaudhary


Title: Prevalence of candidemia in a teaching tertiary care hospital in Haryana


 Incidence of candidemia has increased drastically in last few decades. Candida albicans had been the predominant species responsible till recently, which has now been surpassed by non albicans Candida.

Material and methods:

Blood samples from 4480 patients were cultured on Sabouraud’s Dextrose Agar (SDA) and colonies were identified by standard microbiological techniques.


Candidemia was observed in 6.7% cases. The predominant Candida species isolated in our study was C. albicans (47%) followed by C. tropicalis (22.1%).


New Candida species continue to emerge which makes it imperative to speciate all isolates.


Candida albicans, non albicans candida, antifungal resistance, candidemia, immunocompromised

Full Text:



S. Giri and A. J. Kindo, “A review of Candida species causing blood stream infection,” Indian Journal of Medical Microbiology.2012;30(3):270–278.

Tak V, Mathur P, Varghese P, Gunjiyal J, Xess I, Misra MC. The Epidemiological Profile of Candidemia at an Indian Trauma Care Center J Lab Physicians. 2014;6(2):96–101

Pfaller MA, Diekema DJ. Epidemiology of Invasive Candidiasis: A Persistent Public Health Problem. Clin Microbiol Rev. 2007;20:133–163.

Sobel JD. The emergence of non-albicans Candida species as causes of invasive candidiasis and candidemia. Curr Infect Dis Rep. 2006;8:427–433.

N. Goel, P. K. Ranjan, R. Aggarwal, U. Chaudhary, and N. Sanjeev, “Emergence of nonalbicans Candida in neonatal septicemia and antifungal susceptibility: experience from a tertiary care center,” Journal of Laboratory Physicians.2009;1:53–55.

pfaller MA. Nosocomial Candidiasis: Emerging Species, Reservoirs, and Modes of Transmission. Clinical Infectious Diseases 1996;22(8uppl 2):889-894

Milne LJR. Mackie and McCartney: Practical Medical Microbiology. 14th ed. New York: Churchill Livingstone; 1996. Fungi. In: Collee JG, Fraser AG, Marimon BP, Simmons A, editors; pp. 714–17.

Chander J. Textbook of Medical Mycology. 3rd edition. New Delhi: Mehta Publishers; 2009. Fungal culture media. In: Chander J, editor; pp. 508–13.

Sahni V, Aggarval SK, Singh NP, Anuradha S, Sikdar S, Wadhwa A. Candidemia – An under-recognized nosocomial infection in Indian hospitals. J Assoc Physicians India. 2005;53: 607-11.

Xess I, Jain N, Hasan F, Mandal P, Banerjee U. Epidemiology of Candidemia in a tertiary care centre of North India: 5 year study. Infect. 2007;35:256–59.

Jose A, Rodrigue N, Kusne S, Manez R, Irish W, Linden P, et al. Factors associated with the development of Candidemia and Candidemia related death among liver transplant recipients. Annals of Surgery. 1996;223:70–76.

Zaoutis TE, Prasad PA, Localio AR, et al. Risk Factors and Predictors for Candidemia in Pediatric Intensive Care Unit Patients: Implications for Prevention. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2010;51(5):e38-e45. doi:10.1086/655698.

Conde-Rosa A, Amador R, Perez-Torres D, et al. Candidemia distribution, associated risk factors, and attributed mortality at a University-based medical center. P R Health Sci J. 2010;29:26–29.

Tritipwanit K, Chindamporn A, Suankratay C. Epidemiology of Candidemia at King Chulalongkorn Memorial Hospital, Thailand. J Infect Dis Antimicrobial Agents. 2005;22:59–69

Deorukhkr SC, Santosh S. species distribution and antifungal susceptibility profile of Candida species isolated from bloodstream infections. J Evolution Med and Dental Sci. 2012;1(3)241-245.

Benjamin DK Jr, Stoll BJ, Fanaroff AA, Mc Donald SA, OhW, Higgins RD, et al. National institute of child health and human development neonatal research network. Neonatal candidiasis among extremely low birth weight infants. Risk factors, mortality rates and neurodevelopmental outcomes at 18-22 months. Paediatrics.2006;117: 84-92.

Juyal D, Sharma N, Pal S, Rathaur BK, Sharma N. Emergence of non albicans Candida species in neonatal candidemia. North Am J of Med Sci. 2013; 5(9): 541-545

Shivaprakasha S, Radhakrishnan K, Karim P. Candida spp. other than Candida albicans: A major cause of fungaemia in a tertiary care centre. Indian J Med Microbiol.2007;25:405-407

Roilides E, Farmaki E, Evdoridou J, Francesconi A, Kasai M, Filioti J et al. Candida tropicalis in a neonatal intensive care unit. Epidemiologic and molecular analysis of an outbreak of infection in an uncommon neonatal pathogen. J Clin Microbiol. 2003; 91: 735-741.

Lin, H.C., Lin, H.Y., Su, B.H., Ho, M.W., Ho, C.M., Lee, C.Y. et al. Reporting an outbreak of Candida pelliculosa fungemia in a neonatal intensive care unit. J Microbiol Immunol Infect. 2013; 46: 456–462

Pasqualotto, A.C., Sukiennik, T.C., Severo, L.C., de Amorim, C.S., and Colombo, A.L. An outbreak of Pichia anomala fungemia in a Brazilian pediatric intensive care unit. Infect Control Hosp Epidemiol. 2005; 26: 553–558


  • There are currently no refbacks.