Shilpa Gupta


Introduction – The correlation of intraoperative frozen section diagnosis with final diagnosis on permanent section is an integral part of quality assurance in surgical pathology.

Aims and objectives – To assess the accuracy of frozen section, to detect the number and type of discrepancies and to assess the causes for discrepancies.

Material and Methods – We retrospectively reviewed frozen sections performed in the pathology department at tertiary care hospital during a period of 1 year.The results were compared to the permanent sections to evaluate diagnostic accuracy. Discordant cases were reassessed to find the reasons for discrepancy.

Results and discussion - Total 74 cases were studied by frozen section method and paraffin section method (routine H&E stain) and comparision were made. The overall diagnostic accuracy was 93.2% including the partially correct diagnosis. The incidence of false positive cases was 1.35% while that of false negative cases was 5.40%. Incidence of partially correct diagnosis was 9.45%. There were not any cases of deferred diagnosis.

Conclusion – Frozen section is an accurate and valuable test and can be relied on in surgical managements.Most of the discrepancies can be prevented by providing more clinical information to the pathologist and more accurate sampling.


Frozen section, Histopathology

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