Dr. Smita Sawant, Dr. Nirmala Gaikwad, Dr. Kalpana Hajirnis, Dr. Shumalia Zaheer


Cholecystectomy for gall bladder diseases is the most commonly performed surgical procedure worldwide.
(1) Routine examination of the gall bladder after surgery throws up interesting possibilities including carcinoma.
In the present study total 265 cases were included where 186 (70.18%) were females & 79 (29.82%) were males. The male to female ratio was
1:2.35 in our study.
Age distribution showed maximum patient in the age group of 31-50 years, 57 patients in both the decade Histomorphologically, in our
study maximum cases were of chronic calculous cholecystitis 210 (79.24%) cases followed by chronic cholecystitis 20 (7.54%)cases acute on
chronic cholecystitis13 (4.90%)cases, acute calculous cholecystitis 8 (3.01%) cases.
Out of 265 cases 2 (0.77%) were adenocarcinoma. In our study we found one case of porcelain gall bladder, acute gangrenous cholecystitis,
adenoma gall bladder & acute perforating cholecystitis.
Our study strongly recommends routine histopathological examination of all cholecystectomy specimens.


Gallbladder Lesions, Adenocarcinoma Gall Bladder, Porcelain Gallbladder.

Full Text:



Ivy Sharma, Devajit Choudhury, histopathological patterns of gall bladder diseases with special reference to incidental cases : a hospital based study, Int J Res Med Sci,2015Dec;3(12);3553-3557

Bhanumati Giridharan, P.Madhivadhanam, Gall bladder specimen following cholecystectomy: a resource, Int Surg J,2017 Feb;4(2):598-603.

Underwood J.A.,Recovery plan for histopathology,R Coll Path Bull.2001;113:12-14

Ram Krishan Sharma, Neeraj Bisht, N.S.Neki: Histopathological examination of various lesions of gall bladder in routine 488 cholecystectomy specimens-Ahospital based study, Int.J.Curr.Res.Med.Sci.2017,3(8):112-118.

Naedenstedt H, Mattsson F,El-Serag H,Lagergren J.J,Gallstones & cholecystectomy in relation to risk of intra & extra hepatic cholangiocarcinoma ,Br J Cancer,2012 Feb 28;106(5);1011-5,DOI: 10,1038/ bjc.2011.607. Epub 2012Jan12.

Byars & K.Pursnani, An alternative approach to sending all Gall bladders for Histology following Cholecystectomy? Surgical science,2012,3(1):15.20.

Dr Roshan Verma,Dr Nidhi Binnani, Dr Vanita Kumar, Dr Neelu Gupta, Study of various Histopathogical Lesions in resected Gall bladder specimens: A study in consecutive 898 cholecystectomies,IJSRM//Volume//5//Issue//03//Pages//5216-5221//2017//.

Siddiqui F.G, Memon A.A, Abro AH, Sasoli NA, Ahmad L, Routine histopathology of gall bladder after elective cholecystectomy for gallstones: waste of resources or a justified act? BMC Surg.2013;13(1):26

Fletcher DR, Jones RM, Riordan B, Hardy KJ, Laproscopic cholecystectomy for complicated gallstone disease. Surg Endosc,1992;6(4):179-82.

Kumbhakar D, A Histopathological Study of Cholecystectomy Specimens, JMSCR 2016;4(7):11234-11238.

Makino I, Yamaguchi T, Sato N, Yasui T, Kita I, Yamaguchi, et al , Xanthogranulomatous cholecystitis mimicking gall bladder carcinoma with a false –positive result on fluorodeoxyglucose PET 9,World J Gastroenterol,2009;15 (29);3691-3.

RAORV, Kumar A, Sikora SS, Saxena R, Kapoor VK,; Kumar; Sikora; Saxena; Kapoor (2005), Xanthogranulomatous cholecystitis;differntiation from associated gall bladder carcinoma, Trop Gastroenterol, 2005;26(1):31-3.

McCoy JJ,Vila R, Petrossian G,McCall RA, Reddy KS;Vila, et al. Xanthogranulomatous cholecystitis. Report of two cases, J S C Med Assoc, 1976;72(3):78-9.

Robbins& Cotran, Pathological basis of diseases,Volume II, South Asia Edition, page no.875 to 881.

Preethi Shivanna Puttasubbappa and P. Pallavi, Porcelain Gallbladder Mimmicking Carcinoma Gall bladder – a case Report and Review of Literature, Indian J Surg.2013 Jun; 75(Suppl 1): 208-209

Rooholamini SA, Tehrani NS, Razavi MK,Au, AH, Hansen GC, Ostrzega N, Imaging of gall bladder Carcinoma. Radiographics.1994,14(2):291-306,doi:10,1148/radiographics.14,2.8190955,(Pubmed)( Cross Ref)

Berk RN, Armbuster TG, Saltzstein SL, Carcinoma in the Porcelain gallbladder Radiology,1973;106(1):29-31.doi:10.1148/106.1.29(Pubmed)(Cross Ref).

Rosai And Ackeman’s,Surgical Pathology,Volume I, page no.1035 to 1060.

Sternberg’s, Diagnostic Surgical Pathology, Volume II,6TH Edition, page no.1771 to 1846.

Dr Vipin Kathuria, Dr Shagun, Dr Yudhir Singh, Dr Uma Sharma, Dr Pawan Tiwari, Dr Arun Saxena, Histopathological study of Gall Bladder lesions in Gurugram, Haryana, IOSR Journal of Dental and Medical Sciences( IOSR –JDMS)e-ISSN:2279-0853,p-ISSN:2279-0861,Volue 16, Issue 8Ver.XII(Aug.2017),PP 88-92.

Halidestan T, Enell EL, Kullman E, Borch K. Development of symptoms & Complications in individuals with asymptomatic gall stones, Br J Surg 2004; 91: 734-8.

Khoo JJ, Misran NA, A clinicopathological study of Nine cases of Gallbladder Carcinoma in 1122 Cholecystectomies in Johar, Malaysia, Malaysian J Pathol. 2008, 30(1);21-6.

Sen V, Sankaranarayanan R, Mandal S, Ramakumar AV, Parkin DM, Siddiqui M, Cancer patterns in eastern India; the first report of the Kolkata Cancer registry, Int J Cancer, 2002; 100;86-91.

Vijaya Bharathi, P. Urmila Devi, A. Bhagya Lakshmi, Study of cholcystectomy specimens over a period of one year in tertiary care centre,International Journal of Research in Medical Sciences Bharathi IV et al. Int J Res Med Sci.2017 Mar; 5(3);916-921.


  • There are currently no refbacks.