THE PREVALENCE OF SQUAMOUS CELL CARCINOMA IN DIFFERENT SITES OF ORAL CAVITY AT A TERTIARY REFERRAL CENTRE IN HYDERABAD, TELANGANA – A RETROSPECTIVE 5-YEAR STUDY

Dr Vaishali Narayen, Dr NDVN Shyam, Dr G Kiran Kumar, Dr Nishanth Palakurthi

Abstract


BACKGROUND: The purpose of this study was to determine the prevalence of Oral squamous cell carcinomas
(OSCCs) depending upon the involvement of different sites of oral cavity, its variation with age and gender over a
period of 5 years and to compare with other national and international studies.
MATERIALS AND METHODS: Data for the study were obtained from the reports of patients diagnosed with OSCCs between 2014 and 2018
and the following variables were analyzed: age, gender and anatomical location.
STATISTICAL ANALYSIS: The data was analysed with Statistical Package for Social Sciences (SPSS) for Windows 20.0 (SPSS, Inc. Chicago,
Illinois). The observed data was analyzed by Pearson's Chi square test. Con􀃶dence intervals were set at 95% and values of p < 0.05 were
interpreted as statistically signi􀃶cant.
RESULTS: In a total of 1620 biopsies, OSCCs accounted for 364 cases among all the lesions. Maximum number of cases fell in the age group
of 40-59 years among which 170 were male. The most common site was buccal mucosa followed by lateral border of the tongue.
CONCLUSION: This study provides epidemiological information on OSCCs at an institutional level. The relative frequency of these OSCCs
can be analyzed at a global level to understand their prevalence, incidence biological behavior, and distribution.


Keywords


Oral Squamous Cell Carcinoma, Prevalence, Buccal Mucosa, Gingiva Buccal Carcinoma

Full Text:

PDF

References


Ghantous Y, Yaffi V, Abu-Elnaaj I. Oral cavity cancer:epidemiology and early diagnosis. 2015 jul; 32(3):55-63, 71. Hebrew.

L. A. Torre, F. Bray, R. L. Siegel, J. Ferlay, J. Lortet-Tieulent, and A. Jemal, “Global cancer statistics, 2012,” CA: A Cancer Journal for Clinicians, vol. 65, no. 2, pp. 87–108, 2015.

E. P. Simard, L. A. Torre, and A. Jemal, “International trends in head and neck cancer incidence rates: differences by country, sex and anatomic site,” Oral Oncology, vol. 50, no. 5, pp. 387–403, 2014.

Srivastava R, Sharma R, Singh RB, Wilson DW, Mishra S. Computational Studies and Molecular Dynamics of the Potent Biochemical and Molecular Markers in Relevance to Oral Cancer. Open Nutraceuticals J. 2012; 5: 213-218

Howell RE, Wright BA, Dewar R. Trends in the oral cancer in Nova Scotia from 1983 to 1997. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:205-12.

Rautava J, Luukkaa M, Heikinheimo K, Alin J, Grenman R, Happonen RP. Squamous cell carcinomas arising from different types of oral epithelia differ in their tumor and patient characteristics and survival. Oral Oncol 2007;43:911-9

Jemal, A, Bray, F, Center, MM. Global cancer statistics. CA Cancer J Clin 2011; 61(2): 69–90.

Camisasca DR, Silami MA, Honorato J, et al. Oral squamous cell carcinoma clinicopathological features in patients with and without recurrence. ORL J Otorhinolaryngol Relat Spec, 2011,73:170-176.

Lindenblatt RC, Martinez GL, Silva LE, Faria PS, Camisasca DR, Lourencq SQ. Oral squamous cell carcinoma grading systems-analysis of the best survival predictor. J Oral Pathol Med. 2011;41:34–9.

Omar, EA. The outline of prognosis and new advances in diagnosis of oral squamous cell carcinoma (OSCC): review of the literature. J Oral Oncol 2013; 2013: 13.

Rautava J, Luukkaa M, Heikinheimo K, Alin J, Grenman R, Happonen RP. Squamous cell carcinomas arising from different types of oral epithelia differ in their tumor and patient characteristics and survival. Oral Oncol 2007;43:911-9.

Goldenberg DM. A risk factor for oral and oro-pharyngeal cancer. Oral Oncol 2002; 38: 646-9.

Ajay PR, Ashwinirani SR, Nayak A, Suragimath G,Kamala KA, Sande A, et al. Oral cancer prevalence in Western populationof Maharashtra, India, for a period of 5 years. J Oral Res Rev 2018;10:11-4.

Pathak KA, Gupta S, Talole S, Khanna V, Chaturvedi P, Deshpande MS. Advanced squamous cell carcinoma of lower gingiva-buccal complex: Patterns of spread and failure. Head Neck 2005; 27: 597- 602.

Rivera H, Nikitakis NG, Correnti M, Maissi S, Ponce JG. Oral and oropharyngeal cancer in a Venezuelan population. Acta Odontol Latino Am 2008; 21: 175-80.

More Y, D’Cruz AK. Oral cancer: Review of current management strategies. Natl Med J India 2013; 26: 152-8.

Mehrotra R, Singh M, Gupta RK, Singh M, Kapoor AK. Trends of prevalence and pathological spectrum of head & neck cancers in North India. Indian J Cancer 2005; 42: 89-93.

Tandon P, Dadhich A, Saluja H, Bawane S, Sachdeva S.The prevalence of squamous cell carcinoma in different sites of oral cavity at our Rural Health Care Centre in Loni, Maharashtra – a retrospective 10-year study. Contemp Oncol (Pozn) 2017; 21(2): 178–183

Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL. Global burden of disease and risk factors. The World Bank/Oxford Uni¬versity Press, Washington 2006.


Refbacks

  • There are currently no refbacks.