Dr. Dhruti Patel, Dr. Varun Naik, Dr. Sunil Desai, Dr. Bhavin Patel


Aim: This study was carried out to compare two commonly used anaesthetic induction agents viz. Injection
Propofol and Injection Etomidate in maintaining haemodynamic stability during induction of general anaesthesia
and following oral endotracheal intubation in elective surgery.
Material and Methods: This study was carried out in a tertiary care teaching hospital in 50 patients. Patients were randomly allocated into
two groups of 25 patients each. Group A- Propofol and Group B- Etomidate. Haemodynamic and cardiovascular indicators such as systolic
BP, diastolic BP, mean arterial pressure, heart rate and oxygen saturation of patients were recorded in the room (basal); before induction;
during intubation and 1, 3, 5 & 10 minutes afterwards.
Results: The results were collected, tabulated and analysed using non- paired t test and Chi- square test. The results showed that there was a
signi􀃶cant difference between 2 groups regarding systolic BP, diastolic BP and mean arterial pressure; with patients of Propofol group
showing more hypotension after endotracheal intubation and patients of Etomidate group had more stable blood pressures.
Conclusion: In conclusion, patients receiving Etomidate have more stable haemodynamic condition; if there would be no
contraindications, it could be preferred over Propofol for induction of General anaesthesia.


Etomidate, Propofol, Intubation, Cardiovascular response

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