HOMOCYSTEINE: AN INSTIGATING FACTOR FOR ISCHEMIC STROKE

Dr. Surbhi, Himanshu Gupta

Abstract


AIM: to 􀃶nd the relationship between serum homocysteine levels and risk of ischemic stroke.
MATERIAL AND METHOD: A Hospital based observational study was conducted, in which 50 ischemic stroke
patients and 30 controls were included. Socio-demographic pro􀃶le, history, physical and radiological examination, serum homocysteine
levels were recorded and analyzed by using descriptive statistical methods.
RESULTS: Majority of cases and control were male and were in age group of 50-60 years. Homocysteine levels were observed to be
signi􀃶cantly (p=0.0001) higher among cases (21.69±6.33) compared to controls (11.84±3.88). Serum homocysteine levels are having good
sensitivity (80%) and speci􀃶city (76.7%) in predicting ischemic stroke.
CONCLUSION: Serum homocysteine levels are good predictor of ischemic stroke. But, further studies are needed to search for exact causal
role of increased homocysteine in ischemic stroke patients with larger sample size.


Keywords


Homosysteine, Risk Factor, Ischemic Stroke

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