HEMO-LITH: CORRELATION BETWEEN IRON DEFICIENCY ANEMIA AND CHOLELITHIASIS USING COMPLETE BLOOD COUNTS AS THE SOLE GUIDE-A CASE CONTROL STUDY

Dr. Kalpit Goriwal, Dr. Neel Shah, Dr. Adheesh Goriwal

Abstract


Iron de􀃶ciency anemia has been implicated as one of the factors in the pathogenesis of cholelithiasis.
Micronutrients such as iron, zinc, copper, etc have been shown to be associated with cholelithiasis. Iron is a co-factor
for the enzyme nitric oxide synthase (nos) which is responsible for the production of nitric oxide. Reduced levels of nitric oxide are associated
with dysmotility of gall bladder wall. Also, iron de􀃶ciency has been seen to be associated with bile super saturation in gallbladder. We have
recon􀃶rmed this association with case control study model, using only complete blood count parameters to de􀃶ne iron de􀃶ciency anemia.
This has avoided extra 􀃶nancial burden on the patients which is of utmost importance in the region with compromised socio-economic
statistics.


Keywords


Cholelithiasis, Iron Deficiency Anemia, Nitric Oxide Synthase, Nitric oxide, Bile supersaturation, Mentzer index

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References


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