EFFECTS INTRAVENA AMINOPHYLLINE TO ACCELERATE THE TIME OF RECOVERY ANESTHESI GENERAL IN LAPARATOMIC SURGICAL PATIENTS USING BISPECTRAL INDEX IN HAJI ADAM MALIK MEDAN HOSPITAL

Awang Supriady, Akhyar Hamonangan Nasution, Muhammad Ihsan

Abstract


Surgery is an invasive medical treatment performed to diagnose or treat a disease, injury, or deformity of the body.
To determine the effect of intravenous aminophylline to speed up recovery time after postoperative general
anesthesia in laparatomy surgery patients by using bispectral index at Haji Adam Malik Hospital, Medan. The research method used was a
randomized and double-blind randomized controlled trial. This research was carried out at Haji Adam Malik General Hospital Medan from
June to September 2018. The study population was all subjects who were electively scheduled to undergo abdominal laparotomy with
general anesthesia technique with iso􀃸urane inhalation at Haji Adam Malik General Hospital. The total sample obtained was 46 patients.
The normal test of numerical data was used by 􀃶sher exact test. The research hypothesis was tested using the Mann-Whitney test. In the
study conducted on 46 samples which were divided into 2 groups, it was found that there were signi􀃶cant differences between the two
groups in the value of conscious recovery time in patients with general anesthesia. Based on this study, the results of ketorolac when
recovered consciously with aminophylline average 10.48 minutes were calculated starting from T0 (when administering aminophylline)
and in NaCl 0.9%, the average time of 15.48 minutes was calculated from T0 (when administering aminophylline), which of the two drugs
that are given aminophylline can accelerate conscious recovery time in patients with general anesthesia. In the results of this study it was
found that the use of aminophylline gave a faster recovery time compared to 0.9% NaCl (p <0.05) by shortening the time to almost half,
compared to the average recovery time. Administration of 0.9% NaCl in patients with general anesthesia did not affect recovery time after
general anesthesia was assessed using the bispectral index. Administration of aminophylline in patients with general anesthesia can speed
up recovery time after general anesthesia is assessed using the bispectral index. Administration of aminophylline in patients with general
anesthesia can accelerate recovery time after general anesthesia compared with 0.9% NaCl which was assessed using the bispectral index.


Keywords


Intravenous Aminophylline, Bispectral Index.

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References


Altan A, Turgut N, Yildiz F, Türkmen A, Ustün H. Effects of magnesium sulphate and clonidine on propofol consumption, haemodynamics and postoperative recovery. Br J Anaesth. 2005;94(4): 438-441.

Ashraf A. Dahaba. Different Conditions That Could Result in the Bispectral Index Indicating an Incorrect Hypnotic State. AnesthAnalg. 2005;101:765-773

Basheer R, Strecker RE, Thakkar MM, McCarley RW. Adenosine and sleep-wake regulation. ProgNeurobiol. 2010;73:379–396

Bronco A, Ingelmo PM, Aprigliano M, Turella M, Sahillioglu E, Bucciero M, et al. Xenon anaesthesia produces better early postoperative cognitive recovery than sevofluraneanaesthesia. Eur J Anaesthesiol. 2010;27(10):912–6. doi: 10.1097 /EJA. 0b013e32833b652d. [PubMed: 20523212].

Hupfl M, Schmatzer I, Buzath A, Burger H, Horauf K, Ihra G, et al. The effects of Aminophylline on bispectral index during inhalational and total intravenous anaesthesia. Anaesthesia. 2008;63(6):583–7. doi: 10.1111/j.1365-2044.2008.05445.x. [PubMed: 18279487].

Turan A, Kasuya Y, Govinda R, Obal D, Rauch S, Dalton JE, et al. The effect of Aminophylline on Loss of Consciousness, Bispectral Index, Propofol Requirement, and Minimum Alveolar Concentration of Desflurane in Volunteers. AnesthAnalg. 2010;110(2):449–54. doi: 10.1213/ANE.0b013e3181c6be7e. [PubMed: 19955506]. 16. Pal M, Roy U,

Turan A, Kasuya Y, Govinda R, Obal D, Rauch S, Dalton JE, et al. The Effect of Aminophylline on Loss of Consciousness, Bispectral Index, Propofol Requirement, and Minimum Alveolar Concentration of Desflurane in Volunteers. AnesthAnalg. 2010;110(2):449-454. doi: 10.1213/ ANE.0b013e3181c6be7e

Turan A, Memis D, Karamanlyodthlu B, Pamukcu Z, Sut N. Effect of Aminophylline on Bispectral Index. ActaAnaesthesiol Scand. 2010;48(4):408–11. doi: 10.1111/j.0001-5172.2010.00350.x. [PubMed: 15025600].

Turan A, Memis D, Karamanlioglu B, Colak A, Pamukcu Z, Turan N. Effect of Aminophylline on Recovery from SevofluraneAnaesthesia. Eur J Anaesthesiol. 2002;19(6):452–4. [PubMed: 12094921].

Turan A, Memis¸ D, Karamanly´olu B, Pamukc¸u Z, Su¨t N. Effect of Aminophylline on bispectral index. ActaAnaesthesiologicaScandinavica 2010; 48: 408–11.


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