A PROSPECTIVE OBSERVATION STUDY OF TISSUE NECROSIS IN HEMORRHAGIC STROKE PATIENTS WITH TREATMENT REGIMEN AND OUTCOMES

Vutham Vilasini Soukya, Ginnela Sabitha

Abstract


The hypoxic conditions in the brain of Central nervous system may lead to the death of the tissues. This process is a
form of autolysis that is programmed due to the effect of cells in the brain. It occurs mostly due to trauma,
hypertension, diabetes mellitus, or arteriovenous malformation. In this condition the patient may have severe facial drooling, weakness,
headache, seizures and loss of balance, speech disturbance, nausea and vomiting.
A prospective observational study was carried out in a tertiary care hospital to evaluate tissue necrosis in hemorrhagic stroke patients with
treatment regimen and therapeutic outcomes by the medication.
MATERIALS AND METHODOLOGY:
Sampling method: All the patients of age above 36-70 years suffering with stroke were included in the study.
Study site: The study was conducted in an intensive care unit of 500 bedded tertiary care hospital.
Study procedure: The study was done by collecting data by using patient case sheets, based on that data a questionnaire was prepared
according to the guidelines of WHO and HRQOL. Nearly a data of 72 patients were included in the study with all the details of past medical
history, the treatment regimen and laboratory parameters with frequency were collected.
Study duration: The duration of the study was 12 months (August 2017 to August 2018).
RESULTS: Out of 90 patients, 72 patients cooperated with us and provided the information that was the treatment regimen of stroke,
reasons for admission and the results were discussed.
DISCUSSION: Out of 72 patients in our study who were suffering with hemiplegia the age group of 35- 70 years in which 50-60years was
higher (33.33%). The reasons for the admission of patients were trauma (19.44%), hypertension (15.27), diabetes mellitus (13.88%) and the
co morbidity for the hospitalization was hypertension (51.38%) and diabetes mellitus (34.72%). The treatment regimen for the stroke and
general symptoms are mainly antibiotics, anti platelets, multivitamins.
CONCLUSION: Our study concludes that most of the patients were admitted in the hospital due to trauma and complication of diabetes. So
there is a great need of adoption of various strategies to prevent trauma conditions and complications. As clinical pharmacists, if we counsel
the public regarding their health and lifestyle modi􀃶cations we can reduce the chances of stroke and we also should provide the
information regarding hypertension, diabetes and complications of stroke. The awareness programmes conducted by the government
may also reduce the cases of stroke.


Keywords


Hypoxia, Hemorrhagic stroke, Hypertension, Diabetes mellitus

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