A COMPARATIVE STUDY OF PROPOFOL-KETAMINE AND PROPOFOL-FENTANYL FOR TOTAL INTRAVENOUS ANAESTHESIA FOR SHORT SURGICAL CASES IN PAEDIATRIC PATIENTS

Virendra Singh Raghuvanshi, Sasmita Panda

Abstract


Aims and objective :To compare combinations of  Propofol-Ketamine and Propofol-Fentanyl for total intravenous anesthesia in short surgical cases in pediatric patients. The study also  compared  recovery characteristics and  the incidence of side effects / complications in the groups.

Methodology: The patients were randomly divided into two groups depending upon the drug combination used for Total Intravenous Anaesthesia.

Group I : 30 patients were given i.v. Ketamine followed by Propofol.

Group II: 30 patients were given i.v. Fentanyl followed by Propofol

Recovery characteristics were compared  and  the incidence of side effects and complications in two groups were noted.

Results: The pulse rate  and blood pressure remained near to preinduction value in group I, while in group II  these values  decreased. After induction RR increased in group I but decreased  in group II at 1,3%5 min after induction.None of the patients in both groups were observed to have nausea, vomiting and respiratory depression. . A significant no. of the patients in group II were observed to have either pain on injection site or restlessness.

Conclusion: Propofol-Ketamine and Propofol-Fentanyl combinations provide satisfactory surgical conditions for minor surgical procedures in paediatric patients, but the Propofol-Ketamine combination gives better hemodynamic stability and less restlessness during induction and maintenance of anaesthesia. 


Keywords


Propofol,Ketamine ,Fentanyl , Hemodynamic stability

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References


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