“LIVER DISORDER DURING PREGNANCY: A STUDY OF CLINICAL PROFILE IN A TERTIARY CARE HOSPITAL”

Ashish Zarariya, Yogesh Kamble

Abstract


Background: The spectrum of liver disorder during pregnancy is varied from asymptomatic pregnant woman to a fulminant form with life threatening complications. Commonly liver disorder manifests as jaundice. This study aims to analyze the incidence, risk facors, causes of liver disease, clinical presentation, complications and maternal-fetal outcome.

Methods: A prospective observational type of study conducted on 100 patients with jaundice attending antenatal clinic in our hospital over a period of one year.

Results: A total 100 cases of liver diseases complicating pregnancies were recorded out of 30,096 deliveries (0.33%).Viral hepatitis ( 71%) and HELLP syndrome (21%) accounted for majority of cases. Hepatitis E (38%) was the most common cause of liver disease and leads to high maternal-fetal morbidity and mortality.

Conclusion: Liver disease in pregnancy have a non specific presentation. Appropriate supportive management and policy of early delivery will help in improving maternal and fetal outcomes in pregnant women with liver disease.


Keywords


viral hepatitis, HELLP syndrome, Hepatitis E

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References


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