CORRELATION OF DIABETIC MACULOPATHY WITH THE STAGE OF DIABETIC RETINOPATHY

A. Rohini, Dr. A. Yogeswari

Abstract


Aim: To determine the prevalence of diabetic maculopathy, prevalence of the found type of maculopathy and correlation with the stage of diabetic retinopathy.

Materials and methods:

This was a bidirectional observational cohort study of 100 cases (199 eyes with one single eyed) of type 2 Diabetes with diabetic retinopathy in atleast one eye conducted in Tirunelveli medical college and hospital. Stage of diabetic retinopathy according to Early Treatment Diabetic Retinopathy (ETDRS) grading system was done. Type of maculopathy was documented using fundus fluorescein angiography. Correlation of diabetic retinopathy with the stage of diabetic maculopathy was tested statistically.

Results:

49.61% of maculopathy patients had diabetes for less than 10 years. Diffuse maculopathy (63.57%) was the most common type of maculopathy followed by focal (27.91%), ischaemic (4.65%) and mixed (3.87%) maculopathy. Mixed type of maculopathy was common in the younger age group. Moderate NPDR and severe NPDR showed maximum proportion of patients with maculopathy.

Conclusion:

The study demonstrated significant increase in diabetic maculopathy in the sixth decade. Diffuse maculopathy was the commonest irrespective of the stage of diabetic retinopathy.


Keywords


diabetic maculopathy, macular edema, diabetic retinopathy

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References


Williams, Rhys & Airey, M & Baxter, H & Forrester, J&kennedy-martin, Tessa & Girach, A.(2004). Epidemiology of diabetic retinopathy and macular oedema: A systematic review. Eye (London, England). 18. 963-83. 10.1038/sj.eye.6701476.

Aiello LP, Gardner TW, King GL, Blankenship G, Cavallerano JD, Ferris III FL et al. Diabetic retinopathy. Diabetes Care 1998; 21: 143–15

Chang CJ, Fu CC, Chen MS, Yang CL, Chen YJ, Chuang LM et al. A comparison of newly and previously diagnosed diabetics in Taiwan. J Form Med Assoc 1990; 89: 264–269.

Davis TM, Stratton IM, Fox CJ, Holman RR, Turner RC. UK Prospective Diabetes Study 22. Effect of age at diagnosis on diabetic tissue damage during the first 6 years of NIDDM. Diabetes Care 1997; 20: 1435–1441.

Hu YH, Pan XR, Liu PA, Li GW, Howard BV, Bennett PH. Coronary heart disease and diabetic retinopathy in newly diagnosed diabetes in Da Qing, China: the Da Qing IGT and Diabetes Study. Acta Diabetol 1991; 28: 169–173.

Klein R, Klein BE, Moss SE, Linton KL. The Beaver Dam Eye Study. Retinopathy in adults with newly discovered and previously diagnosed diabetes mellitus. Ophthalmology 1992; 99: 58–62.

Kohner EM, Aldington SJ, Stratton IM, Manley SE, Holman RR, Matthews DR et al. United Kingdom Prospective Diabetes Study 30: diabetic retinopathy at diagnosis of non-insulin-dependent diabetes mellitus and associated risk factors. Arch Ophthalmol 1998; 116: 297-303.

Wan Nazaimoon WM, Letchuman R, Noraini N, Ropilah AR, Zainal M, Ismail I et al. Systolic hypertension and duration of diabetes mellitus are important determinants of retinopathy and microalbuminuria in young diabetics. Res Clin Pract 1999; 46: 213–221.

Wirta OR, Pasternack AI, Oksa HH, Mustonen JT, Koivula TA, Helin HJ et al. Occurrence of late specific complications Epidemiology of DR and MO R Williams et al 980 Eye in type 2 (non-insulin-dependent) diabetes mellitus. J Diabetes Complicat 1995; 9: 177-185.

Ramachandran A, Snehalatha C, Vijay V, Viswanathan M. Diabetic retinopathy at the time of diagnosis of NIDDM in south Indian subjects. Diabetes Res Clin Pract 1996; 32: 111–114.

Wilkinson C. P. (for the Global Diabetic Retinopathy Project Writing Team): Classification of Diabetic Retinopathy: A Proposed International Clinical Disease Severity Grading Scale for Diabetic Retinopathy and Diabetic Macular Edema CME. Position Statement: Diabetic Retinopathy. Available from: http://www.medscape.com/viewprogram/2600.

BekT(1999): Diabetic maculopathy caused by disturbances in retinal vasomotion. Anew hypothesis. Acta Ophthalmol Scand; 77: 376–380.

Chew E. Y., Ferris III F. L. (2006): Nonproliferative diabetic retinopathy. In: Ryan J. S., Hinton R. D., Schachat P. A., Wlkinson C. P., editors. Retina, Vol II, Medical retina, Chapter 67, 4th ed. Elsevier Mosby.

Balasubramanyam M., Rema M., Premanand C. (2002): Biochemical and molecular mechanisms of diabetic retinopathy. Curr Sci; 83 (12).

Klein R, Klein BEK, Moss SE et al, The Wisconsin Epidemiologic Study of Diabetic Retinopathy, Prevalence and risk of diabetic retinopathy when age at diagnosis is 30 0r more years. Arch Ophthal 1984; 102 527-532

. Massin-Korobelnik P., Gaudric A. (1994): La maculopathie diabetic. Revue general. J Fr Ophtalmol; 17(11): 706–732.

Gaudric A., Massin-Korobelnik P. (1993): Diabetic maculopathy: classification,epidemiology, spontaneous outcome, treatment. Diabetes Metab; 19: 442–9.

Sir Stewart Duke Elder, Diseases of Retina, System of Ophthalmology, 1967; Vol - 10, 408- 448

Golubovic-Arsovska, M.(2007). Correlation of diabetic maculopathy and level of diabetic retinopathy. Prilozi/ Makedonska akademija na naukitei umetnostite, Oddelenie za biološkii medicinskinauki = Contributions / Macedonian Academy of Sciences and Arts, Section of Biological and Medical Sciences. 27. 139-50.

Mahfouth A Bamashmus , Diabetic retinopathy, visual impairment and ocular status among patients with diabetes mellitus, Indian Journal of Ophthalmology, 2009, vol.57, 293-298.

Klein R, Klein BE, Moss SE, The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XV. The long-term incidence of macular edema, Ophthalmology, 1995; 102: 7-16.


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