A STUDY OF EPITHELIAL CHANGES IN ADJOINING AREAS IN MODIFIED RADICAL MASTECTOMY SPECIMENS IN CASES OF INFILTRATING DUCT CARCINOMA BREAST

Devika Gupta, Pooja Gupta, Satish Mendonca, Shilajeet Bhattacharya

Abstract


Aim of the Study: e aims and objectives of our research paper was to detect the incidence of epithelial proliferations in
adjoining uninvolved breast in Infiltrating Duct Carcinoma(IDC) cases for which Modified Radical mastectomy was done.
Material and Methods: e study involved analysis of 102 Modified Radical Mastectomy (MRM) specimens of Infiltrating Duct Carcinoma
over a period of 18 months
Results: .e epithelial lesions and the tumor were identified based on morphological criteria and tumor was graded as per Nottingham
modification of the Bloom Richardson system. Statistical analysis involved Correlation if any between the tumor parameters and epithelial
lesions which was determined using Pearsons Chi square test (p < 0.05; significant).
Conclusion: It is recommended that extensive random sampling be done from unaffected quadrants which will make surgical pathologists
aware of premalignant changes existing and their evolution into breast cancer.


Keywords


Benign breast disease, Fibrocystic diseases, Infiltrating duct carcinoma

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