Vinod Shende, Ramji Singh, Sachin Pawar


Chronic renal disease is associated with various complications particularly in later stages. Neuropathy is one of such
complication. ese changes can be diagnosed by various ways; nerve conduction study is most specific amongst them all.
We performed nerve conduction study on 384 chronic kidney disease patients after assessing our inclusion and exclusion criteria. Males and
females of 30 yrs and above were included in the study. Written consent and IEC clearance was obtained. All patients were subjected to
electrophysiological evaluation using RMS EMG EP Mark –II machine. Our results suggested that Prevalence of median, ulnar, tibial and
peroneal neuropathy is 44.01% on right side and 44.53% on left side, 44.79% on right side and 48.70% on left side, 56.51% on right side and 54.95%
on left side, 52.60% on right side and 52.60% on left side respectively. us we conclude that motor nerves of lower limb are more frequently
affected than upper limb.


Chronic renal disease (CKD), motor nerve conduction study, neuropathy

Full Text:



Robert Atkins. The epidemiology of chronic kidney disease. Kidney International, Vol. 67, Supplement 94 (2005), pp. S14–S18.

Ruggenenti P, Schieppati A, Remuzzi G. Progression, remission, regression of chronic renal diseases. Lancet, May 2001; 357(9268):1601-8

Jha V, Garcia G, Iseki K, Li Z, Naicker S, Plattner B, Saran R, Wang AY, Yang CW. Chronic kidney disease: global dimension and perspectives. Lancet, Jul 2013; 382(9888): 260-72.

Ajay K Singh, Youssef MK Farag, Bharati V Mittal, Kuyilan Karai Subramanian, Sai Ram Keithi Reddy,Vidya N Acharya, Alan F Almeida, Anil Channakeshavamurthy, H Sudarshan Ballal, Gaccione P, Rajan Issacs, Sanjiv Jasuja, Ashok L Kirpalani, Vijay Kher, Gopesh K Modi, Georgy Nainan, Jai Prakash,Devinder Singh Rana, Rajanna Sreedhara, Dilip Kumar Sinha, Shah Bharat V, Sham Sunder,Raj K Sharma, Sridevi Seetharam, Tatapudi Ravi Raju and Mohan M Rajapurkar. Epidemiology and risk factors of chronic kidney disease in India – results from the SEEK (Screening and Early Evaluation of Kidney Disease) study. BMC Nephrology 2013, 14:114

Lysaght MJ. Maintenance dialysis population dynamics: Current trends and long-term implication. J Am Soc Nephrol 2002;13:37-40.

Jurice D, Bilic A, Schwarz D, Orsanic D, Gabric M, Spoljaric L, Mihanovic M. Clinical Course of uremic neuropathy in long-term hemodialysis. Coll Antropol 2008; 32: 771-775.

Hegstrom RM, Murray JS, Pendras JP, Burnell JM, Scribner BH. Two year’s experience with periodic hemidialysis in the treatment of chronic uremia. Trans Am Soc Artif Intern Organs 1962; 8: 266-280.

Bodofsky EB, Wu KD, Campellone JV, Greenberg WM, Tomaio AC. Asensitive new median-ulnar technique for diagnosing mild Carpal Tunnel Syndrome. Electromyogr Clin Neurophysiol 2005; 45(3):139-44.

Do Yub Ku, Young Sook Park, Hyun Jung Chang, Sung Rok Kim, Jeoung Whan Ryu, Woo Jin Kim. Depression and Life Quality in Chronic Renal Failure Patients with Polyneuropathy on Hemodialysis. Ann Rehabil Med 2012; 36(5): 702-707.

Vinod Shende, Sachin Pawar, Tanushree Jiwane, A R Chaudhari, Anupama Shende. Study of Motor Nerve Conduction Parameters in Guillain Barre Syndrome Patients of Central India.IJCMR March 2016; 3(3):859-861.

Arum V; Richard K S. Bruce A. Neuropathy axonal Na/K pump function and activity- depened exitability changes in end stage kidney disease. Brain .2006 May (5) 992-999

Khadija Fatima, Abdul Majid. Motor Nerve Conduction Studies in Patients with Chronic Renal failure.Journal of Rawalpindi Medical College (JRMC); 2010; 14(1):11-14

Laaksonen S, Metsarinne K, Voipio-Pulkki LM, Falck B. Neurophysiologic parameters and symptoms in chronic renal failure. Muscle Nerve 2002; 25: 884–90.

Mansouri B, Adybeig B, Rayegani M, Yasami S, Behshad V. Uremic neuropathy and the analysis of electrophysiological changes. Electromyogr Clin Neurophysiol 2001; 41: 107– 15.

Di Paolo B, Di Marco T, Cappelli P, Spisni C, Del Rosso G, Palmieri PF, Evangelista M, Albertazzi A. Electrophysiological aspects of nervous conduction in uremia. Clin Nephrol. May 1988; 29(5): 253-60.

Rachel Nardin, Kristine M. Chapman, Elizabeth M. Raynor. Prevalence of Ulnar Neuropathy in Patients Receiving Hemodialysis. Arch Neurol.2005; 62(2):271-275.


  • There are currently no refbacks.