P. Musa Khan, K. S. Amaravathi, C. Komal


Background: Acute pancreatitis remains a common disorder with devastating consequences. Mortality and morbidity
depends on the severity of the disease. We aimed to evaluate the clinical and etiological prole of patients with acute
Materials and methods: This was a prospective observational study done in the department of Medicine, OGH, Hyderabad, during one year
period from 1st July 2017 to 30th June 2018. Detailed clinical history was recorded and examination and lab investigations were done. Severity
of acute pancreatitis was assessed using Atlanta classication.
Results: in this study 50 patients were included- 48(96%) men and 2(4%) women. The major etiological groups were as follows: alcohol in 74%,
dyslipidemia in 18% and gallstones in 6% of patients. Majority (74%) of the patients were in the age group 21-40 years. Pain abdomen (100%)
was present in all patients. Ascites / pleural effusion (18%) was the most common complication. Most of the patients had mild(48%) to moderate
(36%) acute pancreatitis.
Conclusion: Acute pancreatitis was common in third decade with a male predominance. Alcohol was the most common aetiology. Patients with
acute pancreatitis should be evaluated clinically, biochemically and radiologically as this condition associated with severe systemic and local


Acute pancreatitis, S. Amylase, S. Lipase. Alcohol and pancreatitis.

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Baig SJ, Rahed A, Sanjay Sen. A Prospective study of the aetiology, severity and outcome of acute pancreatitis in Eastern India: Tropical Gastroenterology 2008; 29:20-22.

Boon NA, Colledge NR, Walker BR, Hunter AA (Editors) Davidson's Principles and Practice of Medicine. London Churchill Livingstone, 20th edition. 2006; 904-09

Darwin L. Conwell, Peter Banks, Acute and Chronic Pancreatitis, Harrison’s priniples of internal medicine, 19th edition, page no: 2090-2102.

Bhatia M, Wong FLCaoY,et al. Pathophysiology of acute pancreatitis.Pancreatology 2005; 5: 132-44

Chwistek M, Roberts 1, AmoatengAdjepong Y. Gallstone pancreatitis: a community teaching hospital experience. J ClinGastroenterol 2001; 33:41-44

Lankisch PG, Lowenfels AB, Maisonneuve P. What is the risk of alcoholic pancreatitis in heavy drinkers. Pancreas 2002; 25: 411-12

Yuan G, Al Shali KZ, Hegele RA. Hypertriglyceridemia: its etiology, effects and treatment.' CMAJ 2007; 176: 1113-20

Badalov N, Baradarian R, Iswara K, et al. Drug induced acute pancreatitis: an evidence based review. ClinGastroenterolHepatol 2007;5: 648-61

Neoptolemos JP, Kemppainen EA, Mayer JM,et al. Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study. Lancet 2000; 355:1955-1960.

Khan Z, Vlodov J, Horovitz J, et al. Urinary trypsinogen activation peptide is more accurate than hematocrit in determining severity in patients with acute pancreatitis: a prospective study. Am J Gastroenterol2002; 97:1973-1977.

Balthazar EJ. CT diagnosis and staging of acute pancreatitis. Radiologic Clinics of North America. 1989 Jan;27(1):19-37.

Moynihan B. Acute Pancreatitis. Ann Surg 1925; 81:132-42.

KU Ahmed, MA Ahad et al.,Clinical profile of acute pancreatitis in a teaching hospital. Bang Med J Khulna 2016;49:7-12.

RajshekharPatil, Yallappa, A study of clinical profile in acute pancreatitis and its management, SAS J. Surg. 2017;3(4):94-103

Prasad H.L, T.R. Nargarjuna, clinical profile of patients with acute pancreatitis, Int J Res Med Sci. 2016Jul;4(7):2994-2997.

MD Shakeel, Syed ShahidIrfan, clinical profile of patients with acute pancreatitis, IntSurg J. 2017 Feb;4(2):534-537

Sand J, Välikoski A, Nordback I. Alcohol consumption in the country and hospitalizations for acute alcohol pancreatitis and liver cirrhosis during a 20-year period. Alcohol and alcoholism. 2009 May 1;44(3):321-5.

Kashid A. Acute pancreatitis Experience at Manipal Hospital, Bangalore. Appendix 1-A. Management of acute pancreatitis, by Bhansali SK & Shah SC, Jaslok Hospital. 2006:173 -5

Ranson JHC. Prognostic signs and the role of operative management in 'acute pancreatitis. SurgGynocolobstet 2008; 139: 69-81

Brisando G, Maria G, Ferrante A, Civello IM. Evaluation of prognostic factors in patients with acute pancreatitis. HepaGastroenterol 2009; 46: 1990-97


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