SMEAR EXAMINATION: AN IMPORTANT TOOL IN LEPROSY AND RELAPSE

Jyotika Kalsy, Riya Kaur Kalra, Dania Kaur, Jasleen Kaur

Abstract


BACKGROUND: Since ancient times, leprosy has been regarded as a contagious, disabling and incurable disease. It is
estimated to have disabled one to two million people visibly and irreversibly.
OBJECTIVE: To highlight the need for smear examination in every case of suspected leprosy to prevent relapse and further transmission, and
achieve complete cure.
METHODS: Retrospective analysis of an incidental nding of relapse cases from the 10 year data (April 2005 to March 2015), a study from
Amritsar district.
RESULTS: The relapse rate was found to be 1.95% and on further analysis, it was seen that the MB cases in which the bacterial load was high
before the treatment were the ones that had relapsed.
CONCLUSION: Diagnosing and classifying leprosy solely on the basis of skin lesions as per WHO operational classication may lead to over or
under diagnosis and inadequate treatment which can further cause relapse, spread of infection and resistance.


Keywords


Leprosy; Relapse in leprosy, Smear examination

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References


Misra RS, Kataria JK. Classification. In: Kumar B, Kar HK editors, IAL Textbook of leprosy. 2nd ed. New Delhi: Jaypeebrothers medical publishers (P) Ltd; 2016.

Kaimal S, Thappa DM. Relapse in leprosy. Indian J DermatolVenereolLeprol [serial online] 2009 [cited 2018 Sep 4];75:126-35. Available from: URL: http://www.ijdvl.com/text.asp?2009/75/2/126/48656.

Prasad PVS, Kaviarasan PK. Leprosy therapy, past and present: Can we hope to eliminate it? Indian J Dermatol. Oct-Dec 2010;55(4):316-324.

How to do a skin smear examination for leprosy Learning Guide Three. [Online]. [2018 Sept 04]. Available from: URL: https://www.google.co.in/search?q=ref%3A+How+to+do+a+skin+smear+examination+for+leprosy+Learning+Guide+Three&rlz=1C1CHBD_enIN789IN790&oq=ref%3A+How+to+do+a+skin+smear+examination+for+leprosy+Learning+Guide+Three&aqs=chrome..69i57j69i58.1201j0j7&sourceid=chrome&ie=UTF-8

The final push strategy to eliminate leprosy as a public health problem Questions and Answers, WHO, Geneva. 2nd ed. [Online]. [2018 Sept 04]. Available from: URL: http://www.who.int/lep/resources/Final_Push_%20QA.pdf?ua=1

The Leprosy Unit, WHO. Risk of relapse in leprosy. Indian J Lepr[serial online] 1995 Jan-Mar [cited 2018 Sept 04];67:13-26. Available from: URL:https://www.ncbi.nlm.nih.gov/pubmed/7622926

Kalsy J, Kaur T, Kaur J, Malhotra SK, Kalra RK. Leprosy in northern India during Post elimination era (2005-2015): A retrospective analysis. Indian J Appl Res 2017 Oct;7(10):14-17.

Rao PN. Recent advances in the control programs and therapy of leprosy. Indian J DermatolVenereolLeprol [serial online] 2004 [cited 2018 Sept 04];70:269-76. Available from: URL: http://www.ijdvl.com/text.asp?2004/70/5/269/12834

Poojabylaiah M, Marne RB, Varrikodan R et al.Relapses in Multibacillary leprosy patients after multidrug therapy. Lepr rev (2008) 79, 320-324. Available from: URL: https://www.lepra.org.uk/platforms/lepra/files/lr/Sept08/Lep320-324.pdf

RajkumarDr, Prabu. (2015). Relapse and deformity among 2177 leprosy patients released from treatment with MDT between 2005 and 2010 in South India: A retrospective cohort study. Leprosy review. 86. 345-355. Available from: URL: https://www.researchgate.net/publication/289184287_Relapse_and_deformity_among_2177_leprosy_patients_released_from_treatment_with_MDT_between_2005_and_2010_in_South_India_A_retrospective_cohort_study

Sarkar R, Pradhan S. Leprosy and women. International Journal of Women’s Dermatology. 2016;2(4):117-121. doi:10.1016/j.ijwd.2016.09.001. Available from: URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418961/#bb0170

Shaw IN, Christian M, Jesudasan K, Kurian N, Rao GS. Effectiveness of multidrug therapy in multibacillary leprosy: A long-term follow-up of 34 multibacillary leprosy patients treated with multidrug regimens till skin smear negativity. Lepr Rev. 2003;74:141–7. [PubMed]

Girdhar BK, Girdhar A, Kumar A. Relapses in multibacillary leprosy patients: Effect of length of therapy. Lepr Rev. 2000;71:144–53. [PubMed]


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