THE ROLE OF INTRA-ARTICULAR INJECTION SODIUM HYALURONATE IN REHABILITATION OF OSTEOARTHRITIS KNEE

Vivek S. Chawathe, Anil K. Gaur, Amit S. Mhambre, Vivek J. Pusnake, Ameya D. Joshi, Shaily M. Shah

Abstract


OBJECTIVE: To assess the effect of injection sodium hyaluronate in osteoarthritis knee as an add on treatment to
routine Medication and Physiotherapy.
PATIENTS AND METHODS: 6 month observational study on total 60 patients suffering from primary osteoarthritis knee of grade II and III
according to Kellgren-Lawrence Grading Scale was conducted. Patients were categorized in 2 groups: Group 1 patient opting for intra-articular
injection sodium hyaluronate and Group 2 patients opting only routine line of treatment. Data was collected on demographic features of the
individuals and changes in the VAS scores, KOOS scores and Lequesne index were measured.
RESULTS: Baseline characteristics were similar between the two groups. Group with visco-supplementation showed overall better outcome as
compared to the control group at the end of 6 month. But at the end of 1 month no signicant difference was felt in both the groups regarding the
outcome. There was not much difference in side effect prole in both the groups.
CONCLUSION: a course of 3 sodium hyaluronate injections along with routine medication can improve the outcome of treatment for longer
period.


Keywords


Hyaluronic acid, Osteoarthritis, Intra-articular, Sodium Hyaluronate

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References


Bedson J, Jordan K and Croft P.(2005) The prevalence and history of knee osteoarthritis in general practice: a case–control study. Family Practice; 22: 103–108.

Hadler NM. Knee pain is the malady- not Osteoarthritis. Ann Intern Med 1992; 116: 598-9.

Altman, R, et al.(1986). Arthritis Rheum 29:1039.

Kellgren JH, Lawrence JS.( 1963). Atlas of standard radiographs. Oxford: Blackwell Scientific.

Jianhao Lin, Rujun Li, Xiaozheng Kang, Hu L.(2010).Risk Factors for Radiographic Tibiofemoral Knee Osteoarthritis. The Wuchuan Osteoarthritis Study.International Journal of Rheumatology,6 pages.

Shishir R,VK Sharma, Rajesh C, ST Sivaraman.(2005). Open Label Multicentre Trial on Safety and Efficacy of Intra-articular Hyaluronic acid in the Treatment of Osteoarthritis of the Knee – A prospective study. JIACM, 6(3): 232-5.

T Pham, A Le Henanff, PhRavaud et al.(2004). Evaluation of the symptomatic and structural efficacy of a new hyaluronic acid compound, NRD101, in comparison with diacerein and placebo in a 1 year randomised controlled study in symptomatic knee osteoarthritis.Ann Rheum Dis, 63:1611–1617.

Huskisson EC, Donnelly S.(1999). Hyaluronic acid in the treatment of osteoarthritis of the knee. Rheumatology, 38:602-607.


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