“A CLINICAL STUDY OF CARDIOVASCULAR MANIFESTATIONS OF NEWLY DETECTED HYPOTHYROIDISM PATIENTS’’

Dr. M. Jayasree, Dr. C. Komal, Dr. Raghavendhar A

Abstract


Hypothyroidism has significant cardiovascular manifestations. Overt and sub clinical hypothyroidism both are
associated with cardiovascular dysfunction and with an increased risk of cardiovascular disease.
ObjectivesTo study the clinical profile of cardiovascular system in hypothyroidism.
Methods One Hundred Twenty cases of newly detected primary hypothyroidism were studied from Dec 2015 to Nov 2017. Data was collected
from One Hundred Twenty patients both outpatient and inpatient in this period, treated at Osmania General Hospital, Hyderabad
ResultsThere were 120 patients, 63.3% had symptoms less than 3 months duration. Cardiovascular symptoms were present in less number of
patients. Bradycardia was observed in 7% of the patients. Stage1 hypertension was noticed in 13.3% (diastolic blood pressure). Low voltage
complexes in electrocardiogram were present in 40% study group. Pericardial effusion was present in 16.6% patients.


Keywords


Hypothyroidism; Cardiovascular Changes; Pericardial Effusion; Diastolic Blood Pressure.

Full Text:

PDF

References


Barry KB. Berlcovitz, Patricia Collins. Neck - Thyroid gland. Chapter 31 in the Gray’s Anatomy, 39th Edition, Churchill Livingstone 2005; 560-564)

Guyton C, Arthur. John E Hall. Thyroid Metabolic Hormones. Chapter 76. In text book of Medical Physiology, 11th edition, Saunders 2006; 931-943).

Reed Larsen P, Terry F Davies, Ian D Hay. Thyroid physiology and Diagnostic evaluation of patients with thyroid disorders, Chapter 10, and Hypothyroidism and Thyroiditis, Chapter 12, Williams Text book of Endocrinology, 10th Edition. W.B. Saunders Company 2003; 331-355, 423-446).

Serafino Fazio, Emiliano A. Palmieri, et al. Effects of Thyroid Hormone on the cardio-vascular system. Recent progress in Hormone Research 2004; 59: 31-50).

Irwin Klein, KaieOjamaa. Thyroid Hormone and the Cardiovascular System. N Engl J. Med. 2001; 334 : 7: 501-508)

Obuobie J. Smith, Evans LM, et al. Increased Central Arterial Stiffness in Hypothyroidism. JCEM 2002; 87(10): 4662-4666)

Danzi S, Klein I. Thyroid hormone and the cardiovascular system. Minerva Endocrinol 2004; 29: 139-50)

Agarwal NK, Unnikrishna AG, Singh SK, et al. Sub clinical hypothyroidism. IJEM 2003; V (1): 38-42)

Watanakunakorn C, Robert EH, Titus CE. Myxoedema. Arch Intern Med 1965; 116: 183-89

Ameet Kumar Oswal et al. Reasearch Journal of Pharmaceutical, Biological and Chemical Sciences : RJPBCS 2014 5(3) P966-975

Ramesh K et al, A Study of cardiaovascular involvement in Hypothyroidism, IAIM ,2016: 3(5) 74-80).

ShashiKanth M et al, Indial Journal of basic and applied medical research: March 2015: Vol-4, Issue-2, P.111-116).

Rawat B et al, An echo cardiographic study of cardiac changes in Hypothyroidism and response to treatment. Kathmandu University Medical Journal (2003) Vol. 2, No. 3, Issue 7, 182- 187).


Refbacks

  • There are currently no refbacks.