BACTERIOLOGY OF URINARY TRACT INFECTION AND ANTIBIOTIC SUSCEPTIBILITY PATTERN IN ICU FROM A TERTIARY CARE HOSPITAL

Dr. Meenakshi S. Morey, Dr. Shashikant H. Morey, Dr Brajendra kumar

Abstract


Urinary tract infection is one of the most common bacterial infections seen in clinical practice.The causative agents for
Urinary tract infection vary from place to place and they also vary in their susceptibility and resistance patterns.This study
was done to know the most common causative agents and their susceptibility pattern will help the clinicians to choose the antibiotic for empirical
treatment. This study was done to find out the common bacteria causing UTI and to determine the antibiotic susceptibility pattern of the urinary
pathogens from a tertiary care hospital, A total of 600 mid-stream urine samples from the suspected UTI patients were tested,after culture is
positive on Nutrient agar and MacKonkey’s media colonies were processed on Vitek-2 compact,Biomerieux, for identification and AST with
MIC. The rate of culture positivity in females was 87.82% and in males was 27.92%. E-coli was the most frequently isolated urinary pathogen
(37.95%), followed by Klebsiella(21.41%) and Acinetobacter(10.94%). E-coli was highly sensitive to Nitrofurantoin(81.92%) and
Amikacin(69.88%) and it was highly resistant to Ampicillin(1.0%). Klebsiella was highly sensitive to Impinem and it was highly resistant to
Ampicillin. Gram negative bacilli were the most commonly isolated organisms in UTI.Urinary pathogens showed resistance to commonly used
antibiotics like broad spectrum penicillin and also to third generation cephalosporins,Quinolone drugs. Amongst the Gram negative and Gram
positive organisms isolated Tigecycline was most effective drug.


Keywords


Urinary Tract Infection; Antimicrobial Susceptibility; Urinary Pathogens

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