Dr. Preeti Baghel, Dr. Anita, Dr. Manju Sharma


Introduction: PPH is dened as blood loss of > 500 ml after vaginal delivery or a loss > 1000 ml after caesarean delivery
and > 1500 ml after caesarean hysterectomy.3Majority of maternal deaths about 50-70% occur in postpartum period of
which 45% death occurs in rst 24 hrs of hospital admission, 34.14% dying within 6 hrs of delivery and 22% death occurs within a hour of
admission due to PPH. Three main groups of oxytocic drugs play an important role in management of atonic PPH. They are Oxytocin ,Ergot
Alkaloids, Prostaglandins .
Material and Methods: This is longitudinal type of observational study is conducted in the Department of Obstetrics and Gynaecology at
MCSG , S.M.S. medical college, Jaipur. 126 pregnant women were allocated to one of the three groups of 42 each by chit method. First was
Oxytocin group (Group-A),Second Misoprostol group (Group-B), Third combined misoprostol-oxytocin group (group C)
Results: There is no signicant difference in blood loss in misoprostol or oxytocin alone given in patients. There was signicantly low blood loss
in combined use of lower doses of oxytocin and misoprostol in compared to using higher doses of oxytocin and misoprostol alone.
Conclusions: A synergistic effect of oxytocin and misoprostol allow a reduction in dose for both agent and therefore limit the side effects while
improving the efcacyin reducing blood loss in caserean section.


Post Partum Haemorrhage, Oxytocin, Misoprostol, Blood Loss, Caserean Section.

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