Prevalence and Antimicrobial Susceptibility of Staphylococcus aureus strain from Clinical Isolates at Gwalior Medical College Hospital

Saroj Kothari, Anubhuti Khare, Vaibhav Misra


Present study was undertaken to find the prevalence & antimicrobial sensitivity of Staphylococcus aureus in clinical
isolates in tertiary care hospital. Various samples were collected for isolation & antimicrobial susceptibility testing of
S.aureus. Out of 5000 samples collected 1684 showed growth in culture media. A total of 255 Staphylococcus were isolated & subjected to
antimicrobial susceptibility. High antimicrobial resistance was seen with common antimicrobial agents such as erythromycin, ampicillin,
cefixime & ceftazidime+clavulinic acid as 78%, 71%, 71% & 63% respectively. Mean highest sensitivity to linezolid (84%), vancomycin (83%) &
doxycycline (82%), whereas mean intermediate antibiotic sensitivity to amikacin (77%), levofloxacin (72%), amoxiclav (64%) & piperacillin
(56%) were observed. Present study showed that Staphylococcus aureus (15%) were resistant to commonly used antibiotics & did not show
100% sensitivity to linezolid & vancomycin. us, there is urgent need to regulate use of antibiotics in hospital for preventing the spread of
antimicrobial resistance.


Staphylococcus aureus, antimicrobial resistance, hospital infection, clinical isolates.

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