A comparative analysis of tumor control and normal tissue complication probability in consequential Radiotherapy plans of Carcinoma cervix using 6 MV X-ray and Cobalt -60 gamma rays

Dr. Anoop Kumar Srivastava, Dr. Madhup Rastogi, Dr. S.P. Mishra

Abstract


20 cases of carcinoma cervix were planned on treatment planning system and optimal plan was obtained with the help of dose volume histogram(DVH) which was further utilized for evaluating the plan radiobiologically. The tumor control probability (TCP) and normal tissue complication probability (NTCP) was calculated with the help of BIOPLAN for the total dosage planned includingbrachytherapy.NTCP for rectum and bladder was obtained using Lyman-Kutcher-Burman(LKB) and relative seriality model.  TCPwas evaluated both by BIOPLAN and Brenner’s formula. It was found thatGamma photon of Co-60 couldalso provide equivalent consequential plan   comparable to 6 MV x-rays. Since visual inspection of dose distribution in of DVH or on CT slices can only form the basis to select the optimal treatment plan, it is imperative for objective treatment plan evaluation to deduce the outcome in terms of radiobiological parameters.


Keywords


TCP, NTCP, DVH

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References


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