TO ASSESS AND COMPARE THE ANALGESIC EFFICACY AND SAFETY OF COMBINATION THERAPY OF TRAMADOL WITH DICLOFENAC VERSUS CODEINE WITH DICLOFENAC IN CANCER PAIN MANAGEMENT IN HALDWANI, KUMAUN REGION

DR ATUL BUNDELA, DR REENA BHARDWAJ, DR BHAVANA SRIVASTAVA, DR KAILASH CHANDRA PANDEY, DR SWAROOP R

Abstract


Objectives:To assess the efficacy and safety of combination therapy of Tramadol with Diclofenac versus Codeine with Diclofenac in cancer painmanagement.Methodology:Total 60 number of patients recruited (30 in tramadol group and 30 in codeine group) and followed up at 2nd week and 4th week.Results:It was seen that both drugs were effective in cancer pain management as there was 28.26% decline in mean pain score in group I and 35.84% decline in group II after 4th week. Atotal of 72 adverse drug reactions were foundand observed that group I had more number of reactions (41reactions) than group II (31 reactions).Conclusion:This study confirms that effective pain management can be achieved with the use of oral Tramadol with Diclofenac and Codeine with Diclofenac. Combination of Codeine with Diclofenac causes more adverse effects in comparison to Tramadol with diclofenac.


Keywords


efficacy, adverse drug reaction.

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