SPECTRUM OF RENAL DYSFUNCTION IN CIRRHOTIC PATIENTS OF JHARKHAND

Rohit Keshav, Dr Bindey Kumar, Abhishek Bhardwaj, Manmeet Topno

Abstract


Liver cirrhosis is  a major health problem worldwide.Renal dysfunction is a common and serious complication in patients with decompensated cirrhosis. The study was undertaken to evaluate renal dysfunction in patients of cirrhosis of liver and find out the correlation between renal dysfunction with the graduation of liver disease (assessed by CPS and MELD score).This hospital based observational study was carried on 150 cirrhotic patients admitted in Rajendra Institute of Medical Sciences, Ranchi, Jharkhand. The mean age of cirrhotic patients was 51.38 ± 10.12 years.Of these, majority were males (78.66%). Renal diseases was found to be  present in 28% of cirrhotic patients. Most common type of renal dysfunction in cirrhotic liver patients was AKI (16%)  followed by HRS (8%) and CKD (4%). The most common etiology of cirrhosis was found to be alcoholism(84.66%) followed by Hepatitis B (10.66%) and C virus (4.66%). There was a statistically significant difference of the presentation of renal dysfunction between patients with different stages of liver cirrhosis according to MELD and Child-Pugh scoring system. This study highlights the fact that we should be more vigilant  in treating chronic liver disease patients with regard to their renal function  in order to reduce the mortality and morbidity of such patients.


Keywords


Cirrhosis, Renal Dysfunction, Child – Pugh score

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