STUDY OF CHANGING CD4 CELL COUNT PATTERN IN PREGNANT LADIES ATTENDING ART CENTRE IN AJMER REGION OF RAJASTHAN

Dr. Parul Chaturvedi, Dr. Jyotsna Chandwani, Dr. Geeta Parihar, Dr.C. K Meena

Abstract


Background- HIV/AIDS is one of  most dreadful diseases affecting mankind worldwide. As per NACO, out of these 35,255 were pregnant women (8.6% from Rajasthan). As known so far HIV deteriorates immune system & declines CD4 cell count.In pregnancy immunity is physiologically compromised further affecting CD4cell count. Studies show CD4 is the strongest predictor of disease progression & survival ,besides being cheaper &affordable. There are very few studies done on changing CD4 cell count pattern of HIV positive pregnant women. Keeping this scenario in mind, this study was carried out.

Aims & Objectives- To study CD4 cell count pattern before & during course of treatment in HIV positive pregnant females.

Methodology- A retrospective observational study was done on HIV positive pregnant females attending ART Centre, J.L.N Medical College &Hospital,Ajmer from 1Jan 2015 to 30 May 2017.Absolute CD4 cell count was done using BDFACS Cell Counter based on flow cytometry,done  at time of registeration& after commencement of treatment.

Results & Conclusion- Out of 1649 HIV positive patients reported, 60.7% were males & 39.2%  females. Among females,16.5% were pregnant women.Average CD4 cell count reported Pre-ART was 406 cell/mm3 & Post-ART 548 cells/mm3.Out of total 107 HIV positive pregnant females, 66.4% reported an improvement in CD4 cell count with ART.Thus, understanding the variation in CD4 count in a vulnerable group like pregnant women will provide useful insight on elimination of AIDS related deaths & improving HIV awareness towards spouse testing by launching various NGO programmes.


Keywords


HIV,CD4,Pregnant females

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References


UNAIDS FACSHEET 2017

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