Dr. Bashar Imam Ahmad, Dr. Muzaffari Yasmeen


Background: liver is responsible for the metabolism of the lipid profile. In the cases of acute viral hepatitis the dysfunction of liver lead to dyslipidemia. Present study examined the plasma lipid profile in the cases of acute viral hepatitis.  

 Methods: This is the Hospital-based prospective study on acute viral hepatitis. Sixty cases of acute viral hepatitis and sixty age and sex matched controls was included in study. Routine biochemical investigation for viral marker lipid profile and liver function test was done in the positive viral hepatitis cases. A ‘p value’ <0.05 was considered statistically significant.

Results: no significant difference in the base line characteristic of the case and control (p>0.5).  Jaundice (100%),   anorexia (99%), vomiting (100 %) and dark coloured urine (100%) were the commonest presentations. Serum cholesterol, triglycerides, low density lipoprotein (LDL) were appreciably higher (p<0.01) while high density lipoprotein (HDL) was considerably lesser (p<0.01) in acute viral hepatitis compared to controls.

Conclusion Noteworthy variation of the lipid profile in blood is seen in the cases of acute viral hepatitis. Difference in lipid fractions point out the severity of the liver damage and help in prognosis of the Acute hepatitis patients.


: Acute viral hepatitis, serum lipids, liver function test.

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