S. K. Sundar, Addala Lakshmi Bhavani


In this study a polymer based  nanocarrier platform suitable for encapsulation of  a flavonoid Apigenin (DIONC – Apigenin) applicable for cancer therapy was developed and a morphometric and elemental analysis of the nanoparticle assembly  was done by SEM – EDS. The SEM reports showed that a net with tiny particle hanging on the polymer dextran coated nanocomposite, which reveals the embedding and incorporation of Fe3O4 nanoparticle in dextran polymer film, The iron oxide  nanoparticles increases the electrostatic surface area of the polymer dextran by increasing its folds and changing it into a net and  providing a favorable environment for trapping drugs inside it. In the elememtal maps C,O and Fe was deduced. The DIONC – Apigenin capsule were examined for particle size and zeta potential analysis. The average particle  diameter of the DIONC – apigenin capsule was 208.2nm and the zeta potential of dextran nanoparticle composite and flavonoid was found to be -18.7mV


Iron Oxide Nano particle, Dextran, Apigenin, SEM, EDX

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International Research Journal of Natural and Applied Science .2016; Vol.3(12)


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