Dr.Jayashree Deshkar, Dr.Snigdha Jain, Dr Aditya Brajendra kumar


The estimation of time since death at the time of autopsy has been and remains to be one of the challenges to the Forensic Pathologist.A total of 100 study cases were randomly selected after screening. The pericardial fluid was examined biochemically for enzyme activity of Amylase, Creatine Kinase (CK), Gamma-glutamyl Transferase (GGT) and Lactate Dehydrogenase (LDH) enzymes by photoelectric colorimetry method. The enzyme activity levels so obtained were charted and statistically studied and graphical records obtained against known post-mortem interval. The data thus obtained was analysed with a view to ascertain whether such assays could be of any help to estimate time since death routinely. In this study we observed a positive correlation of all the four enzymes with the time elapsed after death of which rise in CK was found to be statistically significant


Post-mortem interval (Time since death), Pericardial fluid, Enzyme activity, Amylase, Creatine Kinase (CK), Gamma-glutamyl transferase (GGT), Lactate Dehydrogenase (LDH)

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