Osama F. E. x E. Hassanein, Khaled M. Hassanein, Ahmed S. Ahmed, Wafaa E. Soliman, Gamal F. M. Gad


The aim of the study was investigation of ciprofloxacin-resistant bacterial isolates in cases with catheter-associated urinary tract infections (CAUTIs). Study objectives included isolation and identification of the bacterial isolates and determination of their antibiogram.

For ciprofloxacin-resistant strains, the minimal inhibitory concentration was determined; host characteristics were also studied. The causative bacterial uropathogens detected in all the studied cases were headed by Klebsiella spp. (44.8%) followed by Pseudomonas aeruginosa (18.4%), Escherichia coli (17.6%) and Enterococcus species (14.4%). Quinolone resistance was found in 30 out of 100 patients studied (30%) and in  39 out of   125 bacterial isolates (31.2%). The highest rates of quinolone resistance were shown by Pseudomonas and Klebsiella spp. then E. coli. (39.1%, 32.1% and 31.8% respectively). It is noted that quinolone resistance was higher in patients with mixed bacterial infections (55.6%) than in patients with mono-bacterial infection (19.2%), that may suggest that mixed bacterial infection is a risk factors for development of quinolone resistance.


Catheter, urinary, quinolone, resistance, Assuit.

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