A STUDY OF CLINICOBACTERIOLOGICAL PROFILE OF ACNE VULGARIS IN NORTH-INDIA

Dr. Ashok Kumar, Dr. Aastha Sharma, Dr. Mehak Tuli, Dr. Amandeep Riyat

Abstract


Background: Acne is a chronic inflammatory disease of pilosebaceous units. Aim: To assess the various types of lesions in various grades of acne
and to study the microbial flora in various grades of acne. Materials and methods: 200 patients of Acne vulgaris in the age group 15-30 years
attending Dermatology OPD at tertiary care centre of North India were enrolled and Specimen collected were sent to Department of Microbiology
of the same tertiary centre for gram staining and aerobic and anaerobic culture. Results: Grade II acne was found to be the most common type,
Coagulase Negative Staphylococcus (CONS) was most commonly and Micrococcus was least common isolated bacterium. CONS was most
susceptible to cotrimoxazole, Propionibacterium acnes (P. acnes) was most susceptible to fusidic acid and both were least susceptible to
azithromycin.
Conclusion: Acne is frequently encountered in day to day clinical practice. CONS and P. acnes are important microbial agents in pathogenesis of
acne. In clinical practice, the possibility of widespread antibiotic resistance should be borne in mind and careful use of anti-acne treatment regimen
should be done to prevent emergence of resistance.


Keywords


Acne vulgaris, Microbial flora, Antibiotic resistance

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