MATURE T AND NK CELL LYMPHOMAS: A STUDY FROM A TERTIARY CANCER CARE CENTRE

Dr. Premalata C S, Dr. Ashwini Nargund

Abstract


Background: Mature T and NK cell lymphomas are rare aggressive diseases, comprising about 10% to 15% of non-Hodgkin lymphoma (NHL),
showing geographic variation with certain types. A retrospective study was carried out to analyse the distribution and frequency of various types of
mature T and NK/T cell lymphomas diagnosed at our Institute.
Results: 245 cases of mature T and NK cell lymphomas were diagnosed forming nearly 10% of all cases of NHL, with Peripheral T cell lymphoma-
Not otherwise specified(PTCL-NOS) the commonest type, followed by Anaplastic Large Cell Lymphoma (ALCL). Forty seven cases had
extranodal presentation, upper aero digestive tract being the commonest site.
Conclusions: We found a higher incidence of PTCL NOS and ALCL cases and a lower frequency of Angioimmunoblastic T Cell Lymphoma
(AITL) as compared to the western studies.


Keywords


Mature T and NK cells; non Hodgkin lymphoma; Peripheral T cell lymphoma

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