Dr. R. A Jenifer Cynthia, Dr. S. Senthil kumar, Dr. J. Kavitha, Dr. S. Srinivasan, Dr. S. Lakshmisree


Aim: To determine the levels of procalcitonin in Gingival crevicular fluid of Type II diabetic patients with chronic periodontitis.
Materials and Method: Study included 24 males and grouped as Group I (Healthy, n=8), Group II (Chronic periodontitis, n=8) and Group III
(Chronic periodontitis with type II DM, n=8). Plaque scores, bleeding scores, Probing depth, Clinical attachment loss, RBS and HbA1c were
evaluated. GCF procalcitonin levels were analyzed by ELISA.
Results: Significant increase in GCF procalcitonin levels in group III (CP+DM) at p<0.001. Periodontal destruction was more pronounced in
group III (CP+DM) as assessed by periodontal clinical parameters (p<0.001).
Conclusion: GCF procalcitonin reflects the periodontal disease activity in Type II Diabetics with chronic periodontitis and it can be used as a
potential marker in these co-morbid conditions.


Gingival Crevicular Fluid, Periodontitis, Diabetes Mellitus, Procalcitonin

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