“SQUAMOUS CELL CARCINOMA ARISING FROM MATURE CYSTIC TERATOMA OF OVARY”—A RARE CASE REPORT

Dr. Priyatharsini P, Dr. Sankappa. P. Sinhasan, Dr. Ramachandra. V. Bhat, Dr. Sabita P

Abstract


Mature cystic teratoma (MCT) of ovary is most common germ cell tumor. The malignant transformation of the MCT is very rare and it occurs only
in 1 to 2% of the cases. most common malignancy that can arise is Squamous Cell Carcinoma (SCC). Most of the time, the pre-operative diagnosis
will be dermoid cyst of ovary; only histopathological examination of resected specimen and careful sampling of solid area, known as Rokitansky
tubercle will reveal the hidden malignant transformations of MCT. We came across one such a rare malignant transformation of MCT in 45year old
postmenopausal woman, who attended gynecology department for her chronic abdominal pain and abdominal distension.


Keywords


Mature Cystic Teratoma, Squamous Cell Carcinoma, Ovary

Full Text:

PDF

References


Iwasa A, Oda Y, Kaneki E, Ohishi Y, Kurihara S, Yamada T, et al. Squamous cell carcinoma arising in mature cystic teratoma of the ovary: an immunohistochemical analysis of itstumorigenesis. Histopathology 2007;51(1):98–104.

Hirakawa T, Tsuneyoshi M, Enjoji M. Squamous cell carcinoma arising in mature cystic teratoma of the ovary. Clinicopathologic and topographic analysis. Am J SurgPathol 1989;13(5):397–405.

Ayhan A, Bukulmez O, Genc C.Karamursel BS, Ayhan A., Mature cystic teratomas of the ovary: case series from one institution over 34 years. Eur J ObstetGynecolReprodBiol2000;88:153–7.

Hackethal A, Brueggmann D, Bohlmann MK, Franke FE, Tinneberg HR, Münstedt K., Squamouscell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data, Lancet Oncol, 2008;9;1173–80.

Desouki MM, Fadare O, Chamberlain BK, Shakir N, Kanbour-Shakir A. Malignancy associated with ovarian teratomas: frequency, histotypes, and diagnostic accuracy of intraoperative consultation. Annals of Diagnostic Pathology. 2015 Jun 1;19(3):103–6.

Kikkawa F, Nawa A, Tamakoshi K,Hisatake I,Kazuo K,Nobuhiko S, et al, Diagnosis of squamouscell carcinoma arising from mature cystic teratoma of theovary. Cancer, 1998;82:2249–55.


Refbacks

  • There are currently no refbacks.