PRIMARY PULMONARY CHORIOCARCINOMA - A RARE CASE REPORT - DIAGNOSIS AND TREATMENT CHALLENGES

Dr. Sabarinath Ravichandar, Dr. Saravanan MC

Abstract


Primary Pulmonary Choriocarcinoma is a highly malignant intrapulmonary trophoblastic tumour affecting young individuals producing hCG.
These extragonadal choriocarcinomas are unusual in two ways: they are not associated with hydatididform mole, abortions, ectopic gestation or
with normal pregnancy where the infant is normal and are not part of germ cell neoplasm either in the gonads or elsewhere(1). Since the lungs are a
frequent site of metastatic choriocarcinoma with a prevalence of 45% to 87%,(2) the diagnosis of Primary Pulmonary Choriocarcinoma should be
made carefully by exclusion of a primary focus in gonads, mediastinum, retroperitoneum, other midline structures and from non-trophoblastic
malignancies in the lung including conventional primary lung carcinomas which may produce or express ectopic placental hormones. Here we
discuss a similar case of a 28 year old women with Primary Pulmonary Choriocarcinoma.


Keywords


Primary Pulmonary Choriocarcinoma

Full Text:

PDF

References


Dehner LP. Gestational and non-gestational trophoblastic neoplasia: a historic and pathobiologic surgery.

Am J SurgPathol 1980; 4: 43-58

Kumar J, Ilancheran A, Ratnam SS. Pulmonary metastases in gestational trophoblastic diseases: a review of 97 cases. Br J Obstetrics and Gynecology1988; 95: 70-4

Fishman’s Pulmonary Diseases and Disorders 5th edition Volume II 2015; 1794

Review Article: Primary Pulmonary Choriocarcinoma: Is It Still an Enigma? UshaKini and M.K. Babu

Department of Pathology, St. John’s Medical College and Hospital, Koramangala, Bangalore, India


Refbacks

  • There are currently no refbacks.