Dr. Ishan Saini, Dr. Ashish Kumar


Objective: To study the role of Magnetic Resonance Imaging in diagnostic evaluation of pediatric epilepsy.
Methods: The present study was carried out in the Department of Radiodiagnosis, ESIC Medical College & Hospital, Faridabad. The study
included forty five children presented with epilepsy and were referred to our department for brain evaluation.
Results: Abnormal findings on MRI were noted in 39 out of 45 children. The most common abnormality being infectious disease presented in 17
patients which included 10 cases of NCC and 7 patients with intra-cranial tuberculomas. Imaging features of hypoxic ischaemic
encephalopathy(HIE) were noted in 6 patients, 6 patients had imaging features of ADEM(acute disseminated encephalomyelitis), 5 patients had
focal cortical dysplasias, 4 patients had grey matter heterotropias and 1 patient had Sturge-Weber syndrome.
Conclusion: In children diagnosed with epilepsy, neuro-imaging reveals a significant number of serious abnormalities not previously suspected.
MR Imaging plays a significant role in diagnosis, prognostication as well as management of these patients.


epilepsy, children, MRI, seizures

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Chugani HT, Shields WD, Shewmon DA, Olson DM, Phelps ME, Peacock WJ. Infantile spasms: I. PET identifies focal cortical dysgenesis in cryptogenic cases for surgical treatment. Ann Neurol 1990;27:406-413

Engel JJ. The role of neuroimaging in the surgical treatment of epilepsy. Acta Neurol Scand Suppl 1988;1 17:84-89

Jabbari B, Van Nostrand D, Gunderson CH, et al. EEG and neuroimaginglocalization in partial epilepsy. Electroencephalogr C/in Neurophysiol1991;79: 108-113

Jabbari B, Gunderson CH, Wippold F, et al. Magnetic resonance imagingin partial complex epilepsy. Arch Neurol 1986;43:869-872

Latack JT, Abou-Khalil BW, Siegel GJ, Sackellares JC, Gabrielsen TO,Aisen AM. Patients with partial seizures: evaluation by MR. CT, and PETimaging. Radiology 1986;159: 159-163

Ormson MJ, Kispert DB, Sharbrough FW, et ai. Cryptic structural lesionsin refractory partial epilepsy: MR imaging and CT studies. Radiology1986;160:215-219

Kuzniecky R, de Ia Sayette V, Ethier A, et al. Magnetic resonance imaging in temporal lobe epilepsy: pathological correlations. Ann Neurol 1987;22:341 -347

Sharma S, Riviello JJ, Harper MB, Baskin MN. The role of emergent neuroimaging in children with new-onset afebrile seizures. Pediatrics. 2003;111:1–5.

Berg AT, Testa FM, Levy SR, Shinnar S. Neuroimaging in children with newly diagnosed epilepsy: A community-based study. Pediatrics. 2000;106:527–532.

Neurocysticercosis: a major cause of neurological disease worldwide. White AC Jr Clin Infect Dis. 1997 Feb; 24(2):101-13

A. BaggaV. KalraO.P. Ghai Intracranial Tuberculoma: Evaluation and Treatment;Clinical Pediatrics Vol 27, Issue 10, pp. 487 – 490

Smith AS, Weinstein MA, Quencer RM, et al. Association of heterotopic gray matter with seizures: MR imaging. Radiology 1988;1 68:195-198

Kuzniecky R, Garcia JH, Faught E, Morawetz RB. Cortical dysplasia in temporal lobe epilepsy: magnetic resonance imaging correlations. Ann Neurol 1991;29:293-298

Doescher JS, deGrauw TJ, Musick BS, et al. Magnetic resonance imaging and electroencephalographic findings in a cohort of normal children with newly diagnosed seizures. J Child Neurol 2006;21:491–495

Shinnar S, O'Dell C, Mitnick R, Berg AT, Moshe SL. Neuroimaging abnormalities in children with an apparent first unprovoked seizure. Epilepsy Res 2001;43:261–269.

Wyllie E, Gupta A, Lachhwani DK. The treatment of epilepsy, principles & practice. Lippincott Williams & Wilkins. (2006):1009–1029


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