EFFECTIVENESS OF PLATELET RICH PLASMA IN THE TREATMENT OF ANDROGENETIC ALOPECIA

Manimegalai. M, Aarthi B Krishna, N. Paru Priyadharsini, Vidhya Livingston, Hemamalini. R, Padam Kumar. M

Abstract


Platelet Rich Plasma (PRP) is promising bio-technology that is fueling interest in tissue engineering and cellular therapeutics due to presence of
plenty of growth factors. 100 male patients with androgenetic alopecia had completed this study between November 2017 and August 2018. In
accordance with Norwood classification of male pattern baldness, 48 patients belonged to type 2 pattern, 32 patients belonged to type 3, 14 patients
belonged to type 4 and 6 patients belonged to type 5 pattern of baldness. After using double spin technique, a total volume of 2-3cc of PRP was
injected in the desired area of scalp. The treatment was performed monthly once for a period of 6 months. The outcome measures were assessed
initially and at the end of each sitting of PRP and 3 months post completion of treatment. Objectives assessed were patient satisfaction using the
questionnaire, macroscopic photos, hair pull test in the affected areas and follicular density using a dermascope. Results: Before treatment, 90% of
our patients had positive pull test. With completion of 4th session of treatment, the hair pull test turned negative in all the cases. Global photographs
showed a significant improvement in hair volume and quality which was bolstered up by a high overall patient satisfaction at the end of 6 sessions.
Average hair follicle density improved by 18.5 - 27.88 Follicles/cm2. Conclusion: Platelet rich plasma injections are simple and efficient treatment
option with a low cost-benefit ratio. It can be can be added in the treatment armamentarium for androgenetic alopecia, especially in sexually active
males.


Keywords


Platelet rich plasma (PRP), androgenetic alopecia, growth factors

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References


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