HISTOPATHOLOGICAL STUDY OF ENDOMETRIAL CURETTINGS IN ABNORMAL UTERINE BLEEDING : A HOSPITAL BASED STUDY FROM A TERTIARY CARE CENTRE FROM NORTH INDIA.

Dr. Navjot Kaur, Dr. Jagjit S. Chahal, Dr. Sunil Raina

Abstract


INTRODUCTION: The etiology of menstrual dysfunction is quite varied. Therefore histopathology of endometrial samples plays a significant
role in arriving at the etiological basis of menstrual dysfunction. This study was carried out to determine the histopathological pattern of the
endometrium in women of various age groups presenting with abnormal uterine bleeding (AUB).
METHODOLOGY: The current study was conducted on 100 patients attending the Department of Obstetrics and Gynaecology of a tertiary care
hospital in north India with a clinical diagnosis of AUB and undergoing dilatation and curettage (D&C) for the same. A histopathological
examination of the products of D&C was performed.
RESULTS: The chief pattern of AUB was menorrhagia (48%), followed by amenorrhea and postmenopausal bleeding (14% each),
menometrorrhagia (13%), metrorrhagia (8%), polymenorrhea (2%) and oligomenorrhea (1%). Maximum cases (88%) were in the age-group of 21-
50 years. The histopathological patterns in this age group mainly included normal proliferative (20%), secretory (16%) and hyperplasia (19%).
13% cases were pregnancy-related viz. products of conception (POC) or H. mole. The commonest histopathological patterns seen were those of
normal proliferative and secretory endometrium as well as endometrial hyperplasia.
CONCLUSION: Histopathological examination of endometrium is a major diagnostic tool in evaluation of AUB and is therefore, the key to
effective therapy and successful management of AUB.


Keywords


Histopathology, endometrial curettings, D&C, AUB.

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References


Singh MP and Prentice A. Epidemiology of abnormal uterine bleeding. Best Pract Res Clin Obstet Gynaecol 2007;21(6):887-90.

Shwayder JM. Pathophysiology of abnormal uterine bleeding. Obstetrics and Gynecology clinics of North America 2000;27(2):219-34.

Brenner PF. Differential diagnosis of AUB. Am J Obstet Gynecol 1996;175:766–9.

Cooper JM and Erickson ML. Endometrial sampling techniques in the diagnosis of abnormal uterine bleeding. Obstetrics and Gynecology Clinics of North America 2000; 27(2):235-44.

Liza S, Rameshkumar K, Lillian S: Value of endometrial aspiration cytology in assessing endometrial status in symptomatic peri-and postmenopausal women. Indian J Cancer 1999;36(1):57-61.

Vaidya S, Lakhey M, Vaidya S, Sharma PK, Hirachand S, Lama S, KC S. Histopathological pattern of abnormal uterine bleeding in endometrial biopsies. Nepal Med Coll J 2013;15(1):74-7.

Maheshwari V, Chakrabarti AK, Tyagi SP, Sharma R, Alam K, Mohsin S. Endometrial changes in abnormal uterine bleeding JOGI1996;46:389-94.

Jetley S, Rana S, Jairajpuri ZS. Morphological spectrum of endometrial pathology in middle-aged women with atypical uterine bleeding: A study of 219 cases. J Midlife Health2013;4(4):216–20.

Mehrotra VG, Mukerjee K, Pandey M, Samant V. Dysfunctional uterine bleeding (150 cases). JOGI1972;32:680-4.

Lidor A, Ismajovich B, Confino E, David MP. Histopathological findings in 226 women with postmenopausal uterine bleeding. Acta Obstet Gynecol Scand 1986;65:41-3.


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