DIFFERENTIAL ELEMENTAL CHARACTERIZATION OF HOLOPTELEA INTEGRIFOLIA, A PREDICTIVE MEDICAMENT FOR TENNIS ELBOW.

Bhagyajyothi M. Bhat, Sreenivasan KK, Santanu Saha

Abstract


The leaves of Holoptelea integrifolia (H.integrifolia) are suggestive of having analgesic and anti-inflammatory properties, thus useful in the
treatment of tennis elbow. An elementary investigation of the leaf extract was conducted in the present study as the beginning step in understanding
the active ingredients present and correlating them with the suggestive role in curing different ailments. Ethanolic extract of leaves of H.integrifolia
and successive fractionation was done with petroleum ether, chloroform, ethyl acetate, n-butanol and methanol. Phytochemical analysis of
ethanolic and ethyl acetate extracts showed the presence of alkaloids, triterpenoids, saponins, steroids and tannins. Chloroform and n–butanol
extracts showed alkaloids, triterpenoids, saponins and steroids. Triterpenoids, saponins, steroids and tannins are found in metanolic whereas
triterpenoids and steroids in petroleum ether extract. The anti-inflammatory and analgesic activities of alkaloids, triterpenoids, and tannins may be
responsible for the predictive role of H.integrifolia in curing tennis elbow.


Keywords


Holoptelea integrifolia, preliminary phytochemical screening, alkaloids, triterpenoids.

Full Text:

PDF

References


Kumar D., Kumar K., Gupta J., Bishnoi N., and Kumar S. (2012), “A mini review on chemistry and biology of HolopteleaintegrifoliaRoxb. Planch (Ulmaceae)”.Asian Pacific Journal of Tropical Biomedicine,S1200-5.

Sharma S., Khatri P., Pandey A., Jakhetia V., Chaturvedi C.,and Dwivedi N. (2010), “Antidiabetic screening of leaves extract of Holopteleaintegrifolia”. International Journal of Pharmaceutical Research and Development, 2,66-71.

Kalpana, andUpadhyay A. (2010),“Anti-inflammatory evaluation of ethanolic extract of leaves of Holopteleaintegrifolia Planch”. Annals of Biological Research, 1(2),185-195.

Lakshmi K.S., Sharma S.S., Rajesh T., andChitra V. (2010),“Antitumour activity of ethanolic extract of leaves of Holopteleaintegrifolia on Dalton’s ascetic lymphoma in Swiss albino mice”. International journal of green pharmacy, 4:44-47.

Sharma S., Lakshmi K.S., Patidar A., Chaudhary A.,and Dhaker S. (2009),“Studies on anti-inflammatory effect of aqueous extract of leaves of Holopteleaintegrifolia, Planch in rats”. Indian Journal of Pharmacology,41(2),87-88.

Rizwani G.H., Mahmud S., Shareef H., Perveen R., and Ahmed M. (2012), “Analgesic activity of various extracts of Holopteleaintegrifolia (Roxb) planch leaves”. Pakistan Journal of Pharmaceutical Sciences, 25(3),629-632.

Harbone J.B. (1998),“Phytochemical methods: a guide to modern techniques of plant analysis”, 3rd edition Thompson Publishing IT, 5-21.

Flat A.E. (2008), “Tennis elbow”. Proceedings (Baylor University. Medical Center), 21(4),400-402.

Lewis D.A. (1995),“In:Anti-Inflammatory Drugs from Plant and Marine Sources”. BirkhauserVerlag,95-227.

Zhu F., Du B.,and Xu B. (2018),“Anti-inflammatory effects of phytochemicals from fruits, vegetables, and food legumes: A review”.Critical Review on Food Science and Nutrition,58(8),1260-1270.

Eldahshan O.A., andAbdel-Daim M.M. (2015), “Phytochemical study, cytotoxic, analgesic, antipyretic and anti-inflammatory activities of Strychnosnux-vomica”. Cytotechnology, (67)5,831–844.

Ruhil P.,and Minocha N. (2017), “Recent advances in pharmacological potential & phytochemical screening of Holopteleaintegrifolia: a review”. Intrenational Journal of Scientific Research, 6(12),458-459.


Refbacks

  • There are currently no refbacks.