HISTOPATHOLOGICAL SPECTRUM OF URINARY BLADDER LESIONS IN A TERTIARY CARE HOSPITAL: A TWO YEAR PROSPECTIVE STUDY.

Dr. Manish Chaudhry, Dr. Prem Singh

Abstract


BACKGROUND: Urinary bladder lesions, non-neoplastic and neoplastic, are jointly accountable for substantial morbidity and mortality
throughout the world.
OBJECTIVE: Aim of the present study was to analyse the histopathological features of various lesions in bladder biopsies and to study the
frequency of different pathological lesions at a tertiary care institute.
MATERIALS AND METHODS: This was a prospective study done over a period of two year in the Department of Pathology, MMIMSR,
Mullana from 1st April 2016 to 31th March 2018. Histopathological examination of specimens was carried out and the lesions were classified into
various types on light microscopy.
RESULTS: A total of 96 urinary bladder biopsies were studied in a period 2 years. Age of the patients in our study ranged from 21 years to 89 years
with a peak age incidence of cases in 7th decade. Among the 96 cases, 7 were non- neoplastic and 89 were neoplastic lesions. Amongst the 89
neoplastic lesions maximum cases were of urothelial neoplasms.
CONCLUSION: The present study was undertaken mainly to highlight the importance of histopathological examination in the diagnosis of
bladder lesions.


Keywords


Urinary Bladder, Neoplastic, Urothelial Neoplasms.

Full Text:

PDF

References


Mahesh Kumar U and B.R. Yelikar. Spectrum of Lesions in Cystoscopic Bladder Biopsies: A Histopathological study. Al Ameen J Medical Sci. 2012;5:132-136.

Srikousthubha, Sukesh, Raghuveer C.V, Hingle S. Profile of Lesions in Cystoscopic Bladder Biopsies: A Histopathological Study. Journal of Clinical and Diagnostic Research : JCDR. 2013;7(8):1609-1612.

Matalka et al. Transitional cell carcinoma of the urinary bladder – A clinicopathological study. Singapore Med J. 2008;49(10):791.

C.Aparna et al. Histological spectrum of urothelial lesions – experience of a single tertiary care institute. International Journal of Contemporary Medical Research 2016;3(6):1731-3.

Epstein JI, Lotan TL. The Lower Urinary Tract and Male Genital System. In: Kumar V, Abbas AK, Aster JC, editors. Robbins and Cotran Pathologic Basis of Diseases.9thed. Faridabad: Elsevier; 2014. 961-9.

Susmitha et al. A Study on Histopathological Spectrum of Lesions in Urinary Bladder Specimens.Annals of Pathology and Laboratory Medicine. 2018;5(5):489-95.

GrignonDJ . Neoplasm of the urinary bladder. Urologic Surgical Pathology. St Loius: Mosby;1997; 215-305.

Amin MB. APII Urinary bladder biopsy interpretation part-1, College of American pathologists, 2004.

ShruthiHP, Rangaswamy.R. Spectrum of Lesions in Urinary Bladder Biopsies-A HistopathologicalStudy.IJHSR. 2015 May;5(5):144-52

Jecu M, Geavlete B, Multescu R, Stanescu F, Moldoveanu C, Adou L et al. NBI cystoscopy in routine urological practice-from better vision to improve therapeutic management. J Med Life. 2014 June 15;7(2):282-6 .

Young RH, Eble JN M. Non-neoplastic disorders of the urinary bladder, Urologic Surgical Pathology. St Loius: Mosby; 1997;166-212.

Baidya R, Sigdel B, Baidya NL. Histopathological study of cystoscopic bladder biopsies.

Journal of Pathology of Nepal. 2015;5:717-19.

Shah PY, Nanavati M, Patel RG, Goswami HM. Spectrum of lesions in urinary bladder- A histopathological study. Int J Cur Res Rev.2016;8(4):19-24.

Lim M, Adsay NV, Grignon D, Osunkoya AO. Urothelial carcinoma with villoglandular differentiation: a study of 14 cases. Mod Pathol. 2009; 22(10):1280-6.

Vaidya S, Lakhey M, Sabira KC, Hirachand S. Urothelial tumors of the urinary bladder: A histopathological study of cystoscopic biopsies. J Nepal Med Assoc 2013; 52(191): 475-8.

Chinnaswamy R, Krishnamoorthy S, Joseph L, kumaresan N, Ramanan V. Clinico-pathological Study of Bladder Cancer in a Tertiary Care Centre of South India and Impact of Age, Gender, and Tobacco in Causing Bladder Cancer: A Single Centre Experience. Int J Sci Stud. 2016;3(10):72-7.

Sarma KP. On the nature of cystitis follicularis. Journal of Urology 1970; 104:709- 714.

Reuter VE, et al. In: The lower urinary tract: Silverberg’s Diagnostic surgical pathology, second edition, New York: Raven Press Ltd. 1994.

Reuter VE. Bladder - Risk and prognostic factors – a pathologist’s perspective. Urologic Clinics of North America. 1993 August; 26 (3):481-91.

Sharma S, Nath P, Srivastava AN, Singh KM. Tumours of the male urogenital tract: A clinicopathologic study. J Indian Med Assoc; 1994; 92 (11): 357-60.

Dravid NV, Rajeshwari K, KaribasappaGN,et al. Histomorphological profile of lesions in cystoscopic bladder biopsies - a prospective study in North Maharashtra. IntClinPathol J. 2016;3(1):161‒66.

Wynder EC and Goldsmith. The epidemiology of bladder cancer: A second look. Cancer. 1977;40:1246-68.

O’Shea PA, Callaghan JF, Lawlor JB, Reddy VC. ‘Nephrogenic adenoma’: An unusual metaplastic change of urothelium.Journal of Urology.1981;125:249.

F. K. Mostofi.Potentialities of bladder epithelium. The Journal of Urology.1954;71(6):705-14.


Refbacks

  • There are currently no refbacks.