STUDY OF CLINICAL PROFILE OF CONNECTIVE TISSUE DISORDERS

Dr. Hiral A. Halani, Dr. Sneha Vadhvana, Dr. Manish N. Mehta

Abstract


INTRODUCTION: Connective tissue disorders include inherited as well as autoimmune disorders like SLE, RA, MCTD, Scleroderma, Sjogren
syndrome etc. Individuals with autoimmune diseases may have numerous antibodies which eventually lead to multiorgan involvement including
musculoskeletal, cutaneous, renal, cardiopulmonary, neurological involvement. The main stays of management remains glucocorticoids and
immunosuppressants.
METHODOLOGY: A one year cross sectional study was conducted in the Guru Gobind Singh Hospital, Jamnagar. 50 patients of connective
tissue disorders fulfilling the inclusion criteria were included in the study.
RESULTS: In our study, the highest prevalence was noted for SLE ~ 36% followed by RA ~24. We found that the most common presentation of
these disorders was constitutional and musculoskeletal features and the least common being neurological features. We also found an association
between CTDS in females and adverse pregnancy outcomes.


Keywords


Connective Tissue Disorders, Anti-nuclear antibodies

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