Harida Panduwita Sinaga, Oke Rina Ramayani, Johannes Harlan Saing


Background. Urine culture, gold standard of urinary tract infection (UTI), takes time. Alternative parameters are needed. Neutrophil-lymphocyte
ratio (NLR) can be counted from complete blood tests. This study aimed to determine the NLR as bacteria-caused UTI marker in children.
Methods. A cross sectional study in 50 patients with suspected UTI and leukocyturia in Adam Malik and USU Hospital Medan, September 2017 to
January 2018. Urine culture and NLR were taken from all patients. NLR cut off point was determined based on the receiver-operating characteristic
(ROC) curve, with p-value <0.05 was signicant.
Results. Positive urine culture was found in 35 children (70%) with suspected UTI and leukocyturia. ROC analysis showed NLR insignicant to be
used as bacteria-caused UTI marker (p = 0.073). Cut off point of NLR for bacteria-caused UTI was 4.55, with area under curve 0.665 (CI 95%:
Conclusion. NLR cannot be used as bacteria-caused UTI marker in children.


Neutrophil-lymphocyte Ratio, Urinary Tract Infection, Children

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