Diwakar Dhurandhar, Sunita Kalra, Veena Bharihoke


Sucralose is the latest and most popular within the family of artificial sweeteners. It’s rapidly increasing use as a routine table top sweetener among the fitness conscious individuals is attributed to the general notion that it is non caloric substitute of sugar and hence leads to weight loss. But some of the latest research has revealed that it causes weight gain. Thus, the present study was designed to provide an insight into this question of immense societal relevance- Whether sugar free ingestion causes weight gain or weight loss?Six experimental rats were administered sucralose at the dose of 3gm/kg/day for 30 days dissolved in distilled water. Food intake, Water consumption and Weights recorded each day were tabulated and compared between control and experimental groups.Food intake per day was found to be comparable in both the groups. Water intake in experimental rats was more in sucralose treated rats than control ones with p value 0.004. No significant difference in the weights of experimental and control rats was observed.Thepresent study suggests no effect on body weight after sucralose ingestion. But the question whether sucralose causes any change in the body weight and glucose homeostasis needs to be revisited and reinvestigated.


Sucralose, weight loss, obesity, Sugar free

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