TO STUDY CORRELATION OF NEUTROPHIL LYMPHOCYTE RATIO AND DIABETIC RETIONOPATHY IN DIABETES MELLITUS TYPE 2 PATIENTS

Sagar Khandare, Ravi Kumar Patel, Sandeep Pachole

Abstract


INTRODUCTION : Diabetic retinopathy (DR) is a microvascular complication of diabetes. Total white blood cell count is a crude
but sensitive indicator of inflammation and studied in many cardiac and noncardiac diseases as an inflammatory marker such as
acute myocardial infarction, stroke, and heart failure. In this study, the association of neutrophil lymphocyte ratio (NLR) with DR is
studied.
PATIENTS AND METHODS: It is an observational cross sectional study. Totally 115 diagnosed type 2 diabetes mellitus patients
were registered in this study. NLR was calculated by analyzing differential leukocyte count in complete blood picture. Diabetic
retinopathy was detected by doing indirect ophthalmoscopy.
RESULTS: Totally 115 diabetic patients were registered. Out of these, 83 patients had retinopathy and 32 patients did not have
retinopathic changes. Mean NLR for DM2with DR is 2.49+0.94 and in DM2 without DR is 2.06 ± 0.56 which was highly significant
(P = 0.019).
CONCLUSION: The results of our study show that there was a significant relation between NLR and DR. Therefore, NLR may be
considered as a novel surrogate marker of DR in DM2 patients.


Keywords


Diabetic retinopathy(DR), neutrophil lymphocyte ratio (NLR), Diabetes mellitus (DM)

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